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Descriptor English: Transcription Activator-Like Effectors
Descriptor Spanish: Efectores Tipo Activadores de la Transcripción
Descriptor efectores del tipo activadores de la transcripción
Entry term(s) efector TAL
efector similar al activador de la transcripción
efectores TAL
Scope note: Factores de virulencia de bacterias patógenas de plantas, como la especie XANTHOMONAS, que se unen a secuencias específicas en las REGIONES PROMOTORAS del ADN del hospedador para inducir la transcripción de genes específicos del hospedador. Las variaciones en el dominio de unión al ADN de los miembros de la familia de TALE explican las variaciones en la especificidad del ADN. Los dominios de unión al ADN de los TALE se emplean en varias TÉCNICAS GENÉTICAS en las que dichos dominios se fusionan con varios enzimas modificadores del ADN para detectar y manipular determinados sitios de ADN con una secuencia específica.
Descriptor Portuguese: Efetores Semelhantes a Ativadores de Transcrição
Descriptor French: Effecteurs de type activateur de transcription
Entry term(s): Activator-Like Effector, Transcription
Effector, TAL
Effector, Transcription Activator-Like
Effectors, TAL
Effectors, Transcription Activator-Like
TAL Effector
TAL Effectors
Transcription Activator Like Effector
Transcription Activator Like Effectors
Transcription Activator-Like Effector
Tree number(s): D12.776.097.890
D12.776.260.755.700
D12.776.930.900.550
D23.946.896.490
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071336
Scope note: Virulence factors of pathogenic plant bacteria, such as XANTHOMONAS species, that bind to specific sequences in the PROMOTER REGIONS of host DNA to induce transcription of specific host genes. Variations in the DNA binding domain of TALE family members account for the variations in DNA specificity. The TALE DNA-binding domains are used in various GENETIC TECHNIQUES by fusing them with various DNA modifying enzymes to detect and manipulate sequence-specific targeted DNA sites.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56562
Unique ID: D000071336
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2020/05/27
Transcription Activator-Like Effectors - Preferred
Concept UI M000614172
Scope note Virulence factors of pathogenic plant bacteria, such as XANTHOMONAS species, that bind to specific sequences in the PROMOTER REGIONS of host DNA to induce transcription of specific host genes. Variations in the DNA binding domain of TALE family members account for the variations in DNA specificity. The TALE DNA-binding domains are used in various GENETIC TECHNIQUES by fusing them with various DNA modifying enzymes to detect and manipulate sequence-specific targeted DNA sites.
Preferred term Transcription Activator-Like Effectors
Entry term(s) Activator-Like Effector, Transcription
Effector, TAL
Effector, Transcription Activator-Like
Effectors, TAL
Effectors, Transcription Activator-Like
TAL Effector
TAL Effectors
Transcription Activator Like Effector
Transcription Activator Like Effectors
Transcription Activator-Like Effector



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