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Descriptor English: trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride
Descriptor Spanish: Diclorhidrato de trans-1,4-Bis(2-clorobenzaminometil)ciclohexano
Descriptor trans-1,4-bis(2-clorobenzoaminometil)ciclohexano dihidrocloruro
Scope note: Anticolesterolémico que inhibe la delta 7-reductasa, la delta 14-reductasa y la biosíntesis de esteroles.
Descriptor Portuguese: Dicloridrato de trans-1,4-Bis(2-clorobenzaminometil)ciclo-hexano
Descriptor French: Dichlorhydrate de trans-1,4-bis([(2-chlorobenzyl)amino]méthyl)cyclohexane
Entry term(s): A-7, AY9944
AY 9944
AY-9944
AY9944
AY9944 A 7
AY9944 A-7
AY9944-A-7
Tree number(s): D02.455.426.392.368.367.900
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001371
Scope note: An anti-cholesteremic agent that inhibits delta 7-reductase, delta 14 reductase, and sterol biosynthesis.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anticholesteremic Agents
Enzyme Inhibitors
Registry Number: 366-93-8
CAS Type 1 Name: 1,4-Cyclohexanedimethanamine, N,N'-bis((2-chlorophenyl)methyl)-, dihydrochloride, trans-
Previous Indexing: Benzyl Compounds (1972-1974)
Cyclohexanes (1968-1974)
Methylamines (1972-1974)
Public MeSH Note: 2005; see AY-9944 1991-2004; see CYCLOHEXANES 1975-1990
History Note: 2005(1975)
DeCS ID: 1383
Unique ID: D001371
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/11
Revision Date: 2015/11/24
trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride - Preferred
Concept UI M0002055
Scope note An anti-cholesteremic agent that inhibits delta 7-reductase, delta 14 reductase, and sterol biosynthesis.
Preferred term trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride
AY-9944 - Narrower
Concept UI M0464445
Preferred term AY-9944
Entry term(s) A-7, AY9944
AY 9944
AY9944
AY9944 A 7
AY9944 A-7
AY9944-A-7



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