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Descriptor in English: Maraviroc
Descriptor in Spanish: Maraviroc
Descriptor in Portuguese: Maraviroc
Descriptor in French: Maraviroc
Entry term(s): 4,4-Difluoro-N-((1S)-3-(exo-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo(3.2.1)oct-8-yl)-1-phenylpropyl)cyclohexanecarboxamide
Selzentry
UK 427,857
UK 427857
UK-427,857
UK-427857
UK427,857
UK427857
Tree number(s): D02.455.426.392.368.367.726
D03.383.129.799.682
Scope note: A cyclohexane and triazole derivative that acts as an antagonist of the CCR5 RECEPTOR. It prevents infection by HIV-1 virus strains which use CCR5 as a co-receptor for membrane fusion and cellular entry.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 2019 (2005)
DeCS UI: 57699
Descriptor UI: D000077592
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09
Maraviroc - Preferred
Concept UI M0493371
Scope note A cyclohexane and triazole derivative that acts as an antagonist of the CCR5 RECEPTOR. It prevents infection by HIV-1 virus strains which use CCR5 as a co-receptor for membrane fusion and cellular entry.
Preferred term Maraviroc
Entry term(s) 4,4-Difluoro-N-((1S)-3-(exo-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo(3.2.1)oct-8-yl)-1-phenylpropyl)cyclohexanecarboxamide
Selzentry - Narrower
Concept UI M0515080
Preferred term Selzentry
UK-427,857 - Narrower
Concept UI M0487487
Preferred term UK-427,857
Entry term(s) UK 427,857
UK 427857
UK-427857
UK427,857
UK427857



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