| Descriptor English: | Tosylphenylalanyl Chloromethyl Ketone | ||||||
| Descriptor Spanish: |
Clorometilcetona de Tosilfenilalanila
| ||||||
| Descriptor Portuguese: | Tosilfenilalanil Clorometil Cetona | ||||||
| Descriptor French: | N-(1-Benzyl-3-chloroacétonyl)-para-toluènesulfonamide | ||||||
| Entry term(s): |
Chloromethane, Tosylphenylalanyl Chloromethyl Ketone, Tosylphenylalanyl Chlorophenyltosylamidobutanone Ketone, Tosylphenylalanyl Chloromethyl TPCK Tosylphenylalanyl Chloromethane |
||||||
| Tree number(s): |
D02.455.426.559.389.832.710 D02.886.590.887.660 D12.125.065.930 |
||||||
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D014108 | ||||||
| Scope note: | An inhibitor of Serine Endopeptidases. Acts as alkylating agent and is known to interfere with the translation process. |
||||||
| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
||||||
| Pharm Action: |
Alkylating Agents Protein Synthesis Inhibitors Serine Proteinase Inhibitors |
||||||
| Registry Number: | 402-71-1 | ||||||
| CAS Type 1 Name: | Benzenesulfonamide, N-(3-chloro-2-oxo-1-(phenylmethyl)propyl)-4-methyl-, (S)- | ||||||
| Previous Indexing: |
Chlorine (1974) Phenylalanine (1972-1974) Tosyl Compounds (1973-1974) |
||||||
| Public MeSH Note: | 91; was see under AMINO ACID CHLOROMETHYL KETONES 1977-90; was see under PHENYLALANINE 1975-76 |
||||||
| History Note: | 91(75); was see under AMINO ACID CHLOROMETHYL KETONES 1977-90; was see under PHENYLALANINE 1975-76 |
||||||
| DeCS ID: | 14500 | ||||||
| Unique ID: | D014108 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1991/01/01 | ||||||
| Date of Entry: | 1974/11/19 | ||||||
| Revision Date: | 2000/06/22 |
-
-
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
|
|
Tosylphenylalanyl Chloromethyl Ketone
- Preferred
| Concept UI |
M0021715 |
| Scope note | An inhibitor of Serine Endopeptidases. Acts as alkylating agent and is known to interfere with the translation process. |
| Preferred term | Tosylphenylalanyl Chloromethyl Ketone |
| Entry term(s) |
Chloromethane, Tosylphenylalanyl Chloromethyl Ketone, Tosylphenylalanyl Chlorophenyltosylamidobutanone Ketone, Tosylphenylalanyl Chloromethyl TPCK Tosylphenylalanyl Chloromethane |
We want your feedback on the new DeCS / MeSH website
We invite you to complete a survey that will take no more than 3 minutes.
Go to survey
