| Descriptor English: | Chlorthalidone | ||||||
| Descriptor Spanish: | 
                                Clortalidona                                        
                                        
                                                                                                                            
                                            
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| Descriptor Portuguese: | Clortalidona | ||||||
| Descriptor French: | Chlortalidone | ||||||
| Entry term(s): | 
                                    Chlorphthalidolone Chlortalidone Hygroton Oxodoline Phthalamudine Thalitone  | 
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| Tree number(s): | 
                                        D02.065.884.060.050 D02.455.426.559.389.085.050 D02.455.426.559.389.134.500 D02.478.600.500 D02.522.223.500 D02.886.590.700.090.050 D02.886.590.700.365 D03.633.100.513.750.500  | 
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D002752 | ||||||
| Scope note: | A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic. | 
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| Allowable Qualifiers: | 
                                                                        AA                                                            analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine  | 
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| Pharm Action: | 
                                                                                                    Antihypertensive Agents Diuretics Sodium Chloride Symporter Inhibitors  | 
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| Registry Number: | Q0MQD1073Q | ||||||
| CAS Type 1 Name: | Benzenesulfonamide, 2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)- | ||||||
| DeCS ID: | 2804 | ||||||
| Unique ID: | D002752 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1966/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2016/04/25 | 
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                                        CHEMICALS AND DRUGS
 
Organic Chemicals [D02]Organic Chemicals - 
                                    
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals - 
                                    
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals - 
                                    
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals - 
                                    
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals - 
                                    
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals - 
                                    
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals - 
                                    
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds 
| 
                                                             | 
                                
                        
                                                                    
                        Chlorthalidone                                            
                                        - Preferred                                        
                                                                
                                
                        
                        
                        
                                                                    
                        Hygroton                                            
                                        - Narrower                                        
                                                                
                                
                                                                    
                        Thalitone                                            
                                        - Narrower                                        
                                                                
                                
                        
                        
                    
                    
                
                | Concept UI | 
                                        
                                        M0004215 | 
                                
| Scope note | A benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic. | 
| Preferred term | Chlorthalidone | 
| Entry term(s) | 
                                        
                                                                                            Chlorphthalidolone                                                 Chlortalidone Oxodoline Phthalamudine  | 
                                
| Concept UI | 
                                        
                                        M0004216 | 
                                
| Preferred term | Hygroton | 
| Concept UI | 
                                        
                                        M0350891 | 
                                
| Preferred term | Thalitone | 
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