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Descriptor English: Complement C3b Inactivator Proteins
Descriptor Spanish: Proteínas Inactivadoras del Complemento C3b
Descriptor proteínas inactivadoras del complemento C3b
Entry term(s) inactivadores del complemento C3b
Scope note: Proteínas endógenas que inhiben o inactivan el COMPLEMENTO C3B. Incluyen el FACTOR H DEL COMPLEMENTO y el FACTOR I DEL COMPLEMENTO (inactivador de C3b/C4b). Desdoblan o promueven el desdoblamiento de C3b en fragmentos inactivos, por lo que son importantes en la disminución por regulación de la ACTIVACIÓN DEL COMPLEMENTO y su secuencia citolítica.
Descriptor Portuguese: Proteínas Inativadoras do Complemento C3b
Descriptor French: Protéines inhibitrices de la fraction C3b du complément
Entry term(s): C3b Inactivators
C3b Inhibitors
Complement 3b Inactivators
Complement 3b Inhibitors
Complement C3b Inactivators
Complement C3b Inhibitor Proteins
Conglutinogen Activating Factors
Factors, Conglutinogen Activating
Inactivators, C3b
Inactivators, Complement 3b
Inactivators, Complement C3b
Inhibitors, C3b
Inhibitors, Complement 3b
Tree number(s): D12.776.124.486.274.920.325
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003180
Scope note: Endogenous proteins that inhibit or inactivate COMPLEMENT C3B. They include COMPLEMENT FACTOR H and COMPLEMENT FACTOR I (C3b/C4b inactivator). They cleave or promote the cleavage of C3b into inactive fragments, and thus are important in the down-regulation of COMPLEMENT ACTIVATION and its cytolytic sequence.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Complement Inactivating Agents
Previous Indexing: Complement 3 (1975-1977)
Serum Globulins (1970-1977)
Public MeSH Note: 2006; see COMPLEMENT 3B INACTIVATORS 1978-2005
History Note: 2006 (1978)
DeCS ID: 22142
Unique ID: D003180
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1978/01/01
Date of Entry: 1977/05/17
Revision Date: 2005/06/30
Complement C3b Inactivator Proteins - Preferred
Concept UI M0004933
Scope note Endogenous proteins that inhibit or inactivate COMPLEMENT C3B. They include COMPLEMENT FACTOR H and COMPLEMENT FACTOR I (C3b/C4b inactivator). They cleave or promote the cleavage of C3b into inactive fragments, and thus are important in the down-regulation of COMPLEMENT ACTIVATION and its cytolytic sequence.
Preferred term Complement C3b Inactivator Proteins
Entry term(s) C3b Inactivators
C3b Inhibitors
Complement 3b Inactivators
Complement 3b Inhibitors
Complement C3b Inactivators
Complement C3b Inhibitor Proteins
Conglutinogen Activating Factors
Factors, Conglutinogen Activating
Inactivators, C3b
Inactivators, Complement 3b
Inactivators, Complement C3b
Inhibitors, C3b
Inhibitors, Complement 3b



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