| Descriptor English: | Complement C4b-Binding Protein | ||||
| Descriptor Spanish: |
Proteína de Unión al Complemento C4b
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| Descriptor Portuguese: | Proteína de Ligação ao Complemento C4b | ||||
| Descriptor French: | Protéine de liaison à C4b | ||||
| Entry term(s): |
C4b Binding Protein C4b C3b Inactivator Cofactor C4b-Binding Protein C4b-Binding Protein, Complement C4b-C3b Inactivator Cofactor C4bC3bINA Cofactor C4bC3bINA-Cofactor Cofactor, C4b-C3b Inactivator Complement 4b Binding Protein Complement C3b C4b Inactivator Cofactor Complement C3b-C4b Inactivator Cofactor Complement C4b Binding Protein Complement Component 4b Binding Protein Complement Component 4b-Binding Protein Protein, C4b-Binding Protein, Complement C4b-Binding |
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| Tree number(s): |
D12.776.124.486.274.920.662 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D050716 | ||||
| Scope note: | A serum protein that regulates the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It binds as a cofactor to COMPLEMENT FACTOR I which then hydrolyzes the COMPLEMENT C4B in the CLASSICAL PATHWAY C3 CONVERTASE (C4bC2a). |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Pharm Action: |
Complement Inactivating Agents |
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| Previous Indexing: |
Complement Inactivator Proteins (1981-2005) |
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| Public MeSH Note: | 2006 |
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| History Note: | 2006 |
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| Entry Version: | C4BP |
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| DeCS ID: | 50837 | ||||
| Unique ID: | D050716 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 2006/01/01 | ||||
| Date of Entry: | 2005/06/30 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Complement C4b-Binding Protein
- Preferred
| Concept UI |
M0096952 |
| Scope note | A serum protein that regulates the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It binds as a cofactor to COMPLEMENT FACTOR I which then hydrolyzes the COMPLEMENT C4B in the CLASSICAL PATHWAY C3 CONVERTASE (C4bC2a). |
| Preferred term | Complement C4b-Binding Protein |
| Entry term(s) |
C4b Binding Protein C4b C3b Inactivator Cofactor C4b-Binding Protein C4b-Binding Protein, Complement C4b-C3b Inactivator Cofactor C4bC3bINA Cofactor C4bC3bINA-Cofactor Cofactor, C4b-C3b Inactivator Complement 4b Binding Protein Complement C3b C4b Inactivator Cofactor Complement C3b-C4b Inactivator Cofactor Complement C4b Binding Protein Complement Component 4b Binding Protein Complement Component 4b-Binding Protein Protein, C4b-Binding Protein, Complement C4b-Binding |
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