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Descriptor English: Membrane Cofactor Protein
Descriptor Spanish: Proteína Cofactora de Membrana
Descriptor proteína cofactor de membrana
Entry term(s) antígeno CD46
antígenos CD46
Scope note: Receptor del complemento expresado de modo ubicuo que fija el COMPLEMENTO C3B y el COMPLEMENTO C4B y sirve como cofactor para su inactivación. El CD46 interactúa también con una amplia variedad de patógenos y media en la respuesta inmunitaria.
Descriptor Portuguese: Proteína Cofatora de Membrana
Descriptor French: Antigènes CD46
Entry term(s): Antigen, CD46
Antigens, CD46
CD46 Antigen
CD46 Antigens
Common Antigen, Trophoblast-Leukocyte
Trophoblast Leukocyte Common Antigen
Trophoblast-Leukocyte Common Antigen
Tree number(s): D12.776.124.486.274.920.124
D12.776.543.750.705.833.124
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051916
Scope note: A ubiquitously expressed complement receptor that binds COMPLEMENT C3B and COMPLEMENT C4B and serves as a co-factor for their inactivation by COMPLEMENT FACTOR I. It also interacts with a wide variety of pathogens and mediates the immune response.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Pharm Action: Immunologic Factors
Public MeSH Note: 2018; see ANTIGENS, CD46 1987-2017; MEMBRANE COFACTOR PROTEIN was indexed under MEMBRANE GLYCOPROTEINS 1988-2005; under ANTIGENS, CD 1992-2005; under ANTIGENS, DIFFERENTIATION 1990-1991; and under MEMBRANE PROTEINS 1987
History Note: 2018 (1987)
DeCS ID: 50835
Unique ID: D051916
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2017/05/24
Membrane Cofactor Protein - Preferred
Concept UI M0148714
Scope note A ubiquitously expressed complement receptor that binds COMPLEMENT C3B and COMPLEMENT C4B and serves as a co-factor for their inactivation by COMPLEMENT FACTOR I. It also interacts with a wide variety of pathogens and mediates the immune response.
Preferred term Membrane Cofactor Protein
Entry term(s) Antigen, CD46
Antigens, CD46
CD46 Antigen
CD46 Antigens
Common Antigen, Trophoblast-Leukocyte
Trophoblast Leukocyte Common Antigen
Trophoblast-Leukocyte Common Antigen



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