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Descriptor English: DNA, Recombinant
Descriptor Spanish: ADN Recombinante
Descriptor Portuguese: DNA Recombinante
Descriptor French: ADN recombiné
Entry term(s): DNA Research, Recombinant
Genes, Spliced
Joint, Recombination
Recombinant DNA
Recombinant DNA Research
Recombination Joint
Research, Recombinant DNA
Spliced Genes
Tree number(s): D13.444.308.460
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004274
Scope note: Biologically active DNA which has been formed by the in vitro joining of segments of DNA from different sources. It includes the recombination joint or edge of a heteroduplex region where two recombining DNA molecules are connected.
Annotation: IM; /drug eff /ultrastruct permitted; formed by in vitro joining of DNA from 2 different species: do not confuse with RECOMBINATION, GENETIC (within same species); for guidelines for preventing hazards of recombinant DNA research, coord IM with CONTAINMENT OF BIOHAZARDS (IM) if by MeSH definition (procedures, facilities, programs, equipmt, etc.); for ethical, moral or religious aspects of DNA research: coord with specific ethical, moral or religious aspect (IM); for legal aspects, coord with LEGISLATION AS TOPIC (IM), not LEGISLATION, DRUG nor LEGISLATION, MEDICAL
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: DNA (1966-1976)
Recombination, Genetic (1968-1976)
Public MeSH Note: 77
History Note: 77
Related: Genetic Engineering MeSH
Genetic Vectors MeSH
DeCS ID: 22158
Unique ID: D004274
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1977/01/01
Date of Entry: 1977/04/22
Revision Date: 2009/07/10
DNA, Recombinant - Preferred
Concept UI M0006686
Scope note Biologically active DNA which has been formed by the in vitro joining of segments of DNA from different sources. It includes the recombination joint or edge of a heteroduplex region where two recombining DNA molecules are connected.
Preferred term DNA, Recombinant
Entry term(s) Recombinant DNA
Recombinant DNA Research - Related but not broader or narrower
Concept UI M0006688
Preferred term Recombinant DNA Research
Entry term(s) DNA Research, Recombinant
Research, Recombinant DNA
Recombination Joint - Narrower
Concept UI M0006689
Preferred term Recombination Joint
Entry term(s) Joint, Recombination
Genes, Spliced - Broader
Concept UI M0006687
Preferred term Genes, Spliced
Entry term(s) Spliced Genes



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