| Descriptor English: | Immunoglobulin Fab Fragments | ||||||
| Descriptor Spanish: |
Fragmentos Fab de Inmunoglobulinas
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| Descriptor Portuguese: | Fragmentos Fab das Imunoglobulinas | ||||||
| Descriptor French: | Fragments Fab d'immunoglobuline | ||||||
| Entry term(s): |
Fab Fragment Fab Fragment Immunoglobulins Fab Fragment, Immunoglobulin Fab Fragments Fab Fragments, Immunoglobulin Fab Immunoglobulin Fragments Fragment Immunoglobulins, Fab Fragment, Fab Ig Fab Fragments Immunoglobulin Fab Fragment Immunoglobulin Fragments, Fab Immunoglobulins, Fab Immunoglobulins, Fab Fragment |
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| Tree number(s): |
D12.644.541.500.650 D12.776.124.486.485.680.650 D12.776.124.790.651.680.650 D12.776.377.715.548.680.650 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D007140 | ||||||
| Scope note: | Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PO poisoning RE radiation effects TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Pharm Action: |
Immunologic Factors |
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| Previous Indexing: |
Immunoglobulins (1970-1972) |
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| Public MeSH Note: | 2006; was IMMUNOGLOBULINS, FAB 1973-2005 |
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| History Note: | 2006 (1973) |
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| Entry Version: | IG FAB FRAGMENTS |
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| DeCS ID: | 22214 | ||||||
| Unique ID: | D007140 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1973/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Immunoglobulin Fab Fragments
- Preferred
| Concept UI |
M0011126 |
| Scope note | Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN. |
| Preferred term | Immunoglobulin Fab Fragments |
| Entry term(s) |
Fab Fragment Fab Fragment Immunoglobulins Fab Fragment, Immunoglobulin Fab Fragments Fab Fragments, Immunoglobulin Fab Immunoglobulin Fragments Fragment Immunoglobulins, Fab Fragment, Fab Ig Fab Fragments Immunoglobulin Fab Fragment Immunoglobulin Fragments, Fab Immunoglobulins, Fab Immunoglobulins, Fab Fragment |
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