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Descriptor English: Carbamoyl-Phosphate Synthase (Ammonia)
Descriptor Spanish: Carbamoil-Fosfato Sintasa (Amoniaco)
Descriptor carbamoil-fosfato sintasa (amoníaco)
Entry term(s) carbamoil-fosfato sintetasa I
Scope note: Enzima que cataliza la formación de carbamoil-fosfato a partir de ATP, anhídrido carbónico y amoníaco. Esta enzima es específica para la biosíntesis de la arginina y para el ciclo de la urea. La ausencia o falta de esta enzima puede causar la ENFERMEDAD POR DEFICIENCIA DE CARBAMOIL-FOSFATO SINTASA I. EC 6.3.4.16.
Descriptor Portuguese: Carbamoil-Fosfato Sintase (Amônia)
Descriptor French: Carbamoyl-phosphate synthase (ammonia)
Entry term(s): CP Synthase I
Carbamoyl Phosphate Synthetase I
Carbamoyl-Phosphate Synthetase (Ammonia)
Carbamoyl-Phosphate Synthetase I
Carbamoylphosphate Synthetase I
Carbamyl Phosphate Synthase (Ammonia)
Carbamyl-Phosphate Synthase (Ammonia)
Synthase I, CP
Synthetase I, Carbamoyl-Phosphate
Synthetase I, Carbamoylphosphate
Tree number(s): D08.811.464.259.350
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002222
Scope note: An enzyme that catalyzes the formation of carbamoyl phosphate from ATP, carbon dioxide, and ammonia. This enzyme is specific for arginine biosynthesis or the urea cycle. Absence or lack of this enzyme may cause CARBAMOYL-PHOSPHATE SYNTHASE I DEFICIENCY DISEASE. EC 6.3.4.16.
Annotation: /defic: consider CARBAMOYL-PHOSPHATE SYNTHETASE I DEFICIENCY DISEASE
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 6.3.4.16
CAS Type 1 Name: Carbon dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating)
Previous Indexing: Ammonia (1974)
Carbamates (1974)
Phosphotransferases, ATP (1974)
Public MeSH Note: 98; see CARBAMYL PHOSPHATE SYNTHASE (AMMONIA) 1989-97; see LIGASES 1981-88; see PHOSPHOTRANSFERASES, ATP 1975-80
History Note: 98(75)
Entry Version: AMMONIA CP SYNTHASE
Related: Carbamoyl-Phosphate Synthase I Deficiency Disease MeSH
DeCS ID: 2258
Unique ID: D002222
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/06/28
Carbamoyl-Phosphate Synthase (Ammonia) - Preferred
Concept UI M0003332
Scope note An enzyme that catalyzes the formation of carbamoyl phosphate from ATP, carbon dioxide, and ammonia. This enzyme is specific for arginine biosynthesis or the urea cycle. Absence or lack of this enzyme may cause CARBAMOYL-PHOSPHATE SYNTHASE I DEFICIENCY DISEASE. EC 6.3.4.16.
Preferred term Carbamoyl-Phosphate Synthase (Ammonia)
Entry term(s) CP Synthase I
Carbamoyl Phosphate Synthetase I
Carbamoyl-Phosphate Synthetase (Ammonia)
Carbamoyl-Phosphate Synthetase I
Carbamoylphosphate Synthetase I
Carbamyl Phosphate Synthase (Ammonia)
Carbamyl-Phosphate Synthase (Ammonia)
Synthase I, CP
Synthetase I, Carbamoyl-Phosphate
Synthetase I, Carbamoylphosphate



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