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Descriptor English: Monensin
Descriptor Spanish: Monensina
Descriptor Portuguese: Monensin
Descriptor French: Monensin
Entry term(s): Coban
Monensin A Sodium Complex
Monensin Monosodium Salt
Monensin Sodium
Monensin-A-Sodium Complex
Rumensin
Tree number(s): D03.383.312.600
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008985
Scope note: An antiprotozoal agent produced by Streptomyces cinnamonensis. It exerts its effect during the development of first-generation trophozoites into first-generation schizonts within the intestinal epithelial cells. It does not interfere with hosts' development of acquired immunity to the majority of coccidial species. Monensin is a sodium and proton selective ionophore and is widely used as such in biochemical studies.
Annotation:
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antifungal Agents
Antiprotozoal Agents
Coccidiostats
Proton Ionophores
Sodium Ionophores
Registry Number: 906O0YJ6ZP
CAS Type 1 Name: Monensin
Previous Indexing: Antibiotics (1972-1974)
Furans (1974)
Pyrans (1974)
Public MeSH Note: 87; was see under FURANS 1975-86
History Note: 87(75); was see under FURANS 1975-86
DeCS ID: 23319
Unique ID: D008985
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1987/01/01
Date of Entry: 1974/11/19
Revision Date: 2016/05/31
Monensin - Preferred
Concept UI M0014007
Scope note An antiprotozoal agent produced by Streptomyces cinnamonensis. It exerts its effect during the development of first-generation trophozoites into first-generation schizonts within the intestinal epithelial cells. It does not interfere with hosts' development of acquired immunity to the majority of coccidial species. Monensin is a sodium and proton selective ionophore and is widely used as such in biochemical studies.
Preferred term Monensin
Rumensin - Narrower
Concept UI M0014008
Preferred term Rumensin
Coban - Narrower
Concept UI M0353181
Preferred term Coban
Monensin Sodium - Narrower
Concept UI M0330043
Preferred term Monensin Sodium
Entry term(s) Monensin A Sodium Complex
Monensin Monosodium Salt
Monensin-A-Sodium Complex



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