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Descriptor English: Teprotide
Descriptor Spanish: Teprotido
Descriptor teprótido
Scope note: Nonapéptido sintético (Pir-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro) idéntico al péptido del veneno de serpiente Bothrops jararaca. Inhibe la cininasa II y la ANGIOTENSINA I y ha sido propuesto como hipotensor.
Descriptor Portuguese: Teprotida
Descriptor French: Téprotide
Entry term(s): BPP-9a
Bradykinin Potentiating Peptide 9a
Bradykinin-Potentiating Peptide 9a
Enzyme Inhibitor, Nonapeptide-Converting
Nonapeptide Converting Enzyme Inhibitor
Nonapeptide-Converting Enzyme Inhibitor
Peptide 9a, Bradykinin-Potentiating
SQ-20881
Tree number(s): D12.644.456.810
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013722
Scope note: A synthetic nonapeptide (Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro) which is identical to the peptide from the venom of the snake, Bothrops jararaca. It inhibits kininase II and ANGIOTENSIN I and has been proposed as an antihypertensive agent.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Angiotensin-Converting Enzyme Inhibitors
Antihypertensive Agents
Registry Number: C3E5QBF1R6
CAS Type 1 Name: Bradykinin potentiator B, 2-L-tryptophan-3-de-L-leucine-4-de-L-proline-8-L-glutamine-
Previous Indexing: Oligopeptides (1973-1974)
Peptides (1966-1972)
Snakes (1966-1972)
Public MeSH Note: 91; was see under OLIGOPEPTIDES 1981-90, was SQ 20881 see under OLIGOPEPTIDES 1975-80; SQ 20881 was see TEPROTIDE 1981-93; NONAPEPTIDE CONVERTING-ENZYME INHIBITOR was indexed under OLIGOPEPTIDES 1975-93
Online Note: use TEPROTIDE to search SQ 20881 1975-93; use TEPROTIDE (NM) to search NONAPEPTIDE CONVERTING-ENZYME INHIBITOR 1980-93
History Note: 91(81); was see under OLIGOPEPTIDES 1981-90, was SQ 20881 see under OLIGOPEPTIDES 1975-80; SQ 20881 was see TEPROTIDE 1981-93; NONAPEPTIDE CONVERTING-ENZYME INHIBITOR was (NM) 1975-93
DeCS ID: 23477
Unique ID: D013722
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2013/07/08
Teprotide - Preferred
Concept UI M0021171
Scope note A synthetic nonapeptide (Pyr-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro) which is identical to the peptide from the venom of the snake, Bothrops jararaca. It inhibits kininase II and ANGIOTENSIN I and has been proposed as an antihypertensive agent.
Preferred term Teprotide
Entry term(s) BPP-9a
Bradykinin Potentiating Peptide 9a
Bradykinin-Potentiating Peptide 9a
Enzyme Inhibitor, Nonapeptide-Converting
Nonapeptide Converting Enzyme Inhibitor
Nonapeptide-Converting Enzyme Inhibitor
Peptide 9a, Bradykinin-Potentiating
SQ-20881 - Narrower
Concept UI M0373891
Preferred term SQ-20881



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