| Descriptor English: | Leupeptins | ||||
| Descriptor Spanish: |
Leupeptinas
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| Descriptor Portuguese: | Leupeptinas | ||||
| Descriptor French: | Leupeptines | ||||
| Tree number(s): |
D12.644.456.580 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D007976 | ||||
| Scope note: | A group of acylated oligopeptides produced by Actinomycetes that function as protease inhibitors. They have been known to inhibit to varying degrees trypsin, plasmin, KALLIKREINS, papain and the cathepsins. |
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| Annotation: | protease inhib |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Protease Inhibitors |
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| Previous Indexing: |
Oligopeptides (1973-1974) |
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| Public MeSH Note: | 91; was see under OLIGOPEPTIDES 1975-90 |
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| History Note: | 91(75); was see under OLIGOPEPTIDES 1975-90 |
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| DeCS ID: | 8152 | ||||
| Unique ID: | D007976 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 1991/01/01 | ||||
| Date of Entry: | 1974/11/19 | ||||
| Revision Date: | 1999/11/09 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Leupeptins
- Preferred
| Concept UI |
M0012428 |
| Scope note | A group of acylated oligopeptides produced by Actinomycetes that function as protease inhibitors. They have been known to inhibit to varying degrees trypsin, plasmin, KALLIKREINS, papain and the cathepsins. |
| Preferred term | Leupeptins |
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