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Descriptor English: Peptichemio
Descriptor Spanish: Peptiquimio
Descriptor peptiquimio
Scope note: Mezcla de seis oligopéptidos sintéticos, y cada uno de ellos contiene MELFALÁN. Se utiliza como antineoplásico de amplio espectro debido a sus acciones alquilantes y antimetabólicas, pero es tóxico para la médula ósea, sistema gastrointestinal y vasos.
Descriptor Portuguese: Peptiquímio
Descriptor French: Peptichemio
Tree number(s): D02.455.526.728.650.594.690
D12.644.456.726
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010440
Scope note: A mixture of six synthetic oligopeptides, each containing MELPHALAN. It is used as a broad-spectrum antineoplastic due to its alkylating and antimetabolic actions but, is toxic to bone marrow, gastrointestinal system and vasculature.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimetabolites, Antineoplastic
Antineoplastic Agents, Alkylating
Registry Number: 9076-25-9
CAS Type 1 Name: Peptichemio
Previous Indexing: Nitrogen Mustard Compounds (1974)
Peptides (1974)
Public MeSH Note: 91; was see under MELPHALAN 1981-90; was see under NITROGEN MUSTARD COMPOUNDS 1975-80
History Note: 91(75); was see under MELPHALAN 1981-90; was see under NITROGEN MUSTARD COMPOUNDS 1975-80
DeCS ID: 10636
Unique ID: D010440
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2000/06/22
Peptichemio - Preferred
Concept UI M0016214
Scope note A mixture of six synthetic oligopeptides, each containing MELPHALAN. It is used as a broad-spectrum antineoplastic due to its alkylating and antimetabolic actions but, is toxic to bone marrow, gastrointestinal system and vasculature.
Preferred term Peptichemio



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