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Descriptor English: Aminoimidazole Carboxamide
Descriptor Spanish: Aminoimidazol Carboxamida
Descriptor aminoimidazol carboxamida
Scope note: Metabolito de los agentes antineoplásicos BIC y DIC, derivado del imidazol. Este compuesto, tal cual o en forma de ribonucleótido, se utiliza como agente de condensación en la preparación de nucleósidos y nucleótidos. En combinación con el ácido orótico, se utiliza para el tratamiento de hepatopatías.
Descriptor Portuguese: Aminoimidazol Carboxamida
Descriptor French: 5-Amino-imidazole-4-carboxamide
Entry term(s): Ba 2756
Carboxamide, Aminoimidazole
Tree number(s): D03.383.129.308.030
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000620
Scope note: An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. Compounded with orotic acid, it is used to treat liver diseases.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: 360-97-4
CAS Type 1 Name: 1H-Imidazole-4-carboxamide, 5-amino-
Previous Indexing: Imidazoles (1966-1977)
Public MeSH Note: 91; was see under IMIDAZOLES 1978-90
History Note: 91(78); was see under IMIDAZOLES 1978-90
DeCS ID: 630
Unique ID: D000620
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1977/04/15
Revision Date: 2016/05/27
Aminoimidazole Carboxamide - Preferred
Concept UI M0000949
Scope note An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. Compounded with orotic acid, it is used to treat liver diseases.
Preferred term Aminoimidazole Carboxamide
Entry term(s) Carboxamide, Aminoimidazole
Ba 2756 - Narrower
Concept UI M0353205
Preferred term Ba 2756



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