DeCS

Descriptor English:

Serotonin

Descriptor Spanish:

Serotonina

Spanish from Spain

Descriptor	serotonina
Entry term(s)	5-HT 5-hidroxitriptamina
Scope note:	Mensajero y regulador bioquímico, sintetizado a partir del aminoácido esencial L-TRIPTÓFANO. En los humanos se encuentra principalmente en el sistema nervioso central, el tubo digestivo y las plaquetas. La serotonina interviene en diversas funciones fisiológicas importantes icomo la neurotransmisión, la movilidad gastrointestinal, la hemostasia y la integridad cardiovascular. Las múltiples familias de receptores (RECEPTORES DE SEROTONINA) explican su amplio espectro de acciones fisiológicas y la distribución de este mediador bioquímico.

Descriptor Portuguese:

Serotonina

Descriptor French:

Sérotonine

Entry term(s):

5-Hydroxy-tryptamine
5-Hydroxytryptamine
Entéramine
Hydroxy-tryptamine
Hydroxytryptamine

Tree number(s):

D02.092.211.215.801.852
D03.633.100.473.914.814
D23.469.050.650

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D012701

Scope note:

A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.

Annotation:

/antag = SEROTONIN ANTAGONISTS but consider also SELECTIVE SEROTONIN REUPTAKE INHIBITORS

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Entry Combination:

antagonists & inhibitors:Serotonin Antagonists
agonists:Serotonin Receptor Agonists

Pharm Action:

Serotonin Receptor Agonists

Registry Number:

333DO1RDJY

CAS Type 1 Name:

1H-Indol-5-ol, 3-(2-aminoethyl)-