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Descriptor English: Novobiocin
Descriptor Spanish: Novobiocina
Descriptor novobiocina
Entry term(s) estreptonivicina
ácido cristalínico
Scope note: Compuesto antibiótico derivado de Streptomyces niveus. Tiene una estructura química similar a la cumarina. La novobiocina se une a la ADN girasa y bloquea la actividad de la adenosina trifosfatasa (ATPasa). (Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189).
Descriptor Portuguese: Novobiocina
Descriptor French: Novobiocine
Entry term(s): Calcium, Novobiocin
Crystallinic Acid
Monosodium Salt Novobiocin
Novobiocin Calcium
Novobiocin Sodium
Novobiocin, Monosodium Salt
Sodium, Novobiocin
Streptonivicin
Tree number(s): D03.383.663.283.446.139.500
D03.633.100.150.446.139.500
D09.408.554
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009675
Scope note: An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Enzyme Inhibitors
Nucleic Acid Synthesis Inhibitors
Registry Number: 17EC19951N
CAS Type 1 Name: Benzamide, N-(7-((3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-beta-L-lyxo-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl)-4-hydroxy-3-(3-methyl-2-butenyl)-
DeCS ID: 28212
Unique ID: D009675
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Novobiocin - Preferred
Concept UI M0015020
Scope note An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189)
Preferred term Novobiocin
Entry term(s) Crystallinic Acid
Streptonivicin
Novobiocin Calcium - Narrower
Concept UI M0015021
Preferred term Novobiocin Calcium
Entry term(s) Calcium, Novobiocin
Novobiocin Sodium - Narrower
Concept UI M0329989
Preferred term Novobiocin Sodium
Entry term(s) Monosodium Salt Novobiocin
Novobiocin, Monosodium Salt
Sodium, Novobiocin



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