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Descriptor English: Genes, APC
Descriptor Spanish: Genes APC
Descriptor genes APC
Scope note: Genes supresores de tumor localizados en la región 5q21 del brazo largo del cromosoma 5 humano. La mutación de estos genes se asocia a poliposis adenomatosa familiar (POLIPOSIS ADENOMATOSA DEL COLON) y SÍNDROME DE GARDNER y también en algunos cánceres colorrectales. esporádicos.
Descriptor Portuguese: Genes APC
Descriptor French: Gènes APC
Entry term(s): APC Gene
APC Genes
Gene, APC
Genes, Adenomatous Polyposis Coli
Tree number(s): G05.360.340.024.340.375.249.050
G05.360.340.024.340.415.400.050
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017491
Scope note: Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.
Allowable Qualifiers: DE drug effects
ES ethics
PH physiology
RE radiation effects
Previous Indexing: Genes, Suppressor, Tumor (1991-1992)
Polyposis Syndrome, Familial/genetics (1989-1992)
Public MeSH Note: 93
History Note: 93
Related: Adenomatous Polyposis Coli MeSH
Adenomatous Polyposis Coli Protein MeSH
Gardner Syndrome MeSH
DeCS ID: 30718
Unique ID: D017491
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/20
Revision Date: 2008/07/08
Genes, APC - Preferred
Concept UI M0026534
Scope note Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.
Preferred term Genes, APC
Entry term(s) APC Gene
APC Genes
Gene, APC
Genes, Adenomatous Polyposis Coli



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