Descriptor English: Guanfacine
Descriptor Spanish: Guanfacina
Descriptor guanfacina
Scope note: Agente antihipertensivo de acción central. Disminuye la presión arterial sistólica y diastólica mediante activación de los receptores adrenérgicos alfa-2 del sistema nervioso central, lo que da lugar a depresión del simpático y consecuente redución del tono vascular. Sus reacciones adversas comprenden sequedad bucal, sedación y estreñimiento.
Descriptor Portuguese: Guanfacina
Descriptor French: Guanfacine
Entry term(s): BS 100 141
Guanfacine Hydrochloride
Guanfacine Monohydrochloride
Hydrochloride, Guanfacine
Monohydrochloride, Guanfacine
Tree number(s): D02.078.370.465
RDF Unique Identifier:
Scope note: A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antihypertensive Agents
Adrenergic alpha-2 Receptor Agonists
Registry Number: 30OMY4G3MK
CAS Type 1 Name: Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-
Previous Indexing: Adrenergic alpha Agonists (1969-1990)
Antihypertensive Agents (1966-1990)
Guanidines (1966-1990)
Phenylacetates (1966-1990)
Public MeSH Note: 91
History Note: 91
DeCS ID: 28972
Unique ID: D016316
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1990/05/29
Revision Date: 2013/07/08
Guanfacine - Preferred
Concept UI M0024935
Scope note A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
Preferred term Guanfacine
Tenex - Narrower
Concept UI M0350961
Preferred term Tenex
Guanfacine Hydrochloride - Narrower
Concept UI M0350963
Preferred term Guanfacine Hydrochloride
Entry term(s) Guanfacine Monohydrochloride
Hydrochloride, Guanfacine
Monohydrochloride, Guanfacine
Lon798 - Narrower
Concept UI M0350962
Preferred term Lon798
BS-100-141 - Narrower
Concept UI M0024936
Preferred term BS-100-141
Entry term(s) BS 100 141
Estulic - Narrower
Concept UI M0350964
Preferred term Estulic

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