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Descriptor English: Guanidine
Descriptor Spanish: Guanidina
Descriptor guanidina
Entry term(s) clorhidrato de guanidina
cloruro de guanidinio
guanidinio
hidrocloruro de guanidina
Scope note: Base orgánica fuerte que existe principalmente como iones guanidínicos a pH fisiológico. Se encuentra en la orina como producto normal del metabolismo de las proteínas. Se utiliza en investigaciones de laboratorio como desnaturalizador de proteínas. (Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed). Se usa también en el tratamiento de la miastenia y como sonda fluorescente en cromatografía líquida de alta presión (HPLC).
Descriptor Portuguese: Guanidina
Descriptor French: Guanidine
Entry term(s): Chloride, Guanidinium
Chloride, Guanidium
Guanidine Hydrochloride
Guanidine Monohydrate
Guanidine Monohydrobromide
Guanidine Monohydrochloride
Guanidine Monohydroiodine
Guanidine Nitrate
Guanidine Phosphate
Guanidine Sulfate
Guanidine Sulfate (1:1)
Guanidine Sulfate (2:1)
Guanidine Sulfite (1:1)
Guanidinium
Guanidinium Chloride
Guanidium Chloride
Hydrochloride, Guanidine
Monohydrate, Guanidine
Monohydrobromide, Guanidine
Monohydrochloride, Guanidine
Monohydroiodine, Guanidine
Nitrate, Guanidine
Phosphate, Guanidine
Sulfate, Guanidine
Tree number(s): D02.078.370.472
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019791
Scope note: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: JU58VJ6Y3B
Previous Indexing: Guanidines (1974-1997)
Public MeSH Note: 98; GUANIDINE was indexed under GUANIDINES 1974-97
History Note: 98; use GUANIDINE (NM) 1974-97
DeCS ID: 33385
Unique ID: D019791
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2013/07/08
Guanidine - Preferred
Concept UI M0029365
Scope note A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
Preferred term Guanidine
Entry term(s) Guanidinium
Guanidine Monohydrate - Narrower
Concept UI M0329110
Preferred term Guanidine Monohydrate
Entry term(s) Monohydrate, Guanidine
Guanidine Monohydrobromide - Narrower
Concept UI M0329106
Preferred term Guanidine Monohydrobromide
Entry term(s) Monohydrobromide, Guanidine
Guanidine Monohydroiodine - Narrower
Concept UI M0329105
Preferred term Guanidine Monohydroiodine
Entry term(s) Monohydroiodine, Guanidine
Guanidine Sulfite (1:1) - Narrower
Concept UI M0329112
Preferred term Guanidine Sulfite (1:1)
Guanidine Phosphate - Narrower
Concept UI M0329104
Preferred term Guanidine Phosphate
Entry term(s) Phosphate, Guanidine
Guanidine Sulfate - Narrower
Concept UI M0329103
Preferred term Guanidine Sulfate
Entry term(s) Sulfate, Guanidine
Guanidine Sulfate (1:1) - Narrower
Concept UI M0329111
Preferred term Guanidine Sulfate (1:1)
Guanidine Sulfate (2:1) - Narrower
Concept UI M0329109
Preferred term Guanidine Sulfate (2:1)
Guanidine Hydrochloride - Narrower
Concept UI M0329107
Preferred term Guanidine Hydrochloride
Entry term(s) Chloride, Guanidinium
Chloride, Guanidium
Guanidine Monohydrochloride
Guanidinium Chloride
Guanidium Chloride
Hydrochloride, Guanidine
Monohydrochloride, Guanidine
Guanidine Nitrate - Narrower
Concept UI M0329108
Preferred term Guanidine Nitrate
Entry term(s) Nitrate, Guanidine



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