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Descriptor English: Mitoguazone
Descriptor Spanish: Mitoguazona
Descriptor mitoguazona
Entry term(s) metilglicoxal bis(guanilhidrazona)
Scope note: Agente antineoplásico efectivo contra la leucemia mieloide en animales experimentales. Actúa también como inhibidor de la S-adenosilmetionina descarboxilasa animal.
Descriptor Portuguese: Mitoguazona
Descriptor French: Mitoguazone
Entry term(s): MGBG
Methyl gag
Methyl-gag
Methylgag
Methylglyoxal Bis(guanylhydrazone)
NSC 32946
NSC-32946
NSC32946
Tree number(s): D02.078.370.600
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008935
Scope note: Antineoplastic agent effective against myelogenous leukemia in experimental animals. Also acts as an inhibitor of animal S-adenosylmethionine decarboxylase.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents
Enzyme Inhibitors
Registry Number: OD5Q0L447W
CAS Type 1 Name: Hydrazinecarboximidamide, 2,2'-(1-methyl-1,2-ethanediylidene)bis-
Previous Indexing: Amidines (1973-1974)
Glyoxal (1973-1974)
Hydrazones (1973-1974)
Public MeSH Note: 86; was see under GUANIDINES 1975-85
History Note: 86(75); was see under GUANIDINES 1975-85
DeCS ID: 9125
Unique ID: D008935
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1986/01/01
Date of Entry: 1974/11/19
Revision Date: 2013/07/08
Mitoguazone - Preferred
Concept UI M0013946
Scope note Antineoplastic agent effective against myelogenous leukemia in experimental animals. Also acts as an inhibitor of animal S-adenosylmethionine decarboxylase.
Preferred term Mitoguazone
Entry term(s) MGBG
Methylglyoxal Bis(guanylhydrazone)
NSC-32946 - Narrower
Concept UI M0350966
Preferred term NSC-32946
Entry term(s) NSC 32946
NSC32946
Methyl-gag - Related but not broader or narrower
Concept UI M0013945
Preferred term Methyl-gag
Entry term(s) Methyl gag
Methylgag



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