| Descriptor English: | 3-Iodobenzylguanidine | ||||||
| Descriptor Spanish: |
3-Yodobencilguanidina
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| Descriptor Portuguese: | 3-Iodobenzilguanidina | ||||||
| Descriptor French: | 3-Iodobenzyl-guanidine | ||||||
| Entry term(s): |
(3-Iodo-(131I)benzyl)guanidine 123I Labeled 3-Iodobenzylguanidine 125I Labeled 3-Iodobenzylguanidine 3 Iodobenzylguanidine 3 Iodobenzylguanidine, 123I Labeled 3 Iodobenzylguanidine, 125I Labeled 3-Iodobenzylguanidine, 123I Labeled 3-Iodobenzylguanidine, 125I Labeled Iobenguane Iobenguane (131I) MIBG m Iodobenzylguanidine m-Iodobenzylguanidine meta Iodobenzylguanidine meta-Iodobenzylguanidine |
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| Tree number(s): |
D02.078.370.510 D02.455.426.559.389.454.300 D02.455.526.581.496.300 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D019797 | ||||||
| Scope note: | A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Antineoplastic Agents Enzyme Inhibitors Radiopharmaceuticals |
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| Registry Number: | 35MRW7B4AD | ||||||
| Previous Indexing: |
Guanidines (1980-1982) Iodobenzenes (1983-1997) |
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| Public MeSH Note: | 98; 3-IODOBENZYLGUANIDINE was indexed under IODOBENZENES 1983-97 & GUANIDINES 1980-82 |
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| History Note: | 98; use 3-IODOBENZYLGUANIDINE (NM) 1980-97 |
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| DeCS ID: | 33386 | ||||||
| Unique ID: | D019797 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1998/01/01 | ||||||
| Date of Entry: | 1997/06/20 | ||||||
| Revision Date: | 2013/07/08 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals
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3-Iodobenzylguanidine
- Preferred
Iobenguane (131I)
- Narrower
3-Iodobenzylguanidine, 125I Labeled
- Narrower
(3-Iodo-(131I)benzyl)guanidine
- Narrower
3-Iodobenzylguanidine, 123I Labeled
- Narrower
| Concept UI |
M0029373 |
| Scope note | A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase. |
| Preferred term | 3-Iodobenzylguanidine |
| Entry term(s) |
3 Iodobenzylguanidine Iobenguane MIBG m Iodobenzylguanidine m-Iodobenzylguanidine meta Iodobenzylguanidine meta-Iodobenzylguanidine |
| Concept UI |
M0029375 |
| Preferred term | Iobenguane (131I) |
| Concept UI |
M0331308 |
| Preferred term | 3-Iodobenzylguanidine, 125I Labeled |
| Entry term(s) |
125I Labeled 3-Iodobenzylguanidine 3 Iodobenzylguanidine, 125I Labeled |
| Concept UI |
M0029374 |
| Preferred term | (3-Iodo-(131I)benzyl)guanidine |
| Concept UI |
M0331309 |
| Preferred term | 3-Iodobenzylguanidine, 123I Labeled |
| Entry term(s) |
123I Labeled 3-Iodobenzylguanidine 3 Iodobenzylguanidine, 123I Labeled |
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