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Descriptor English: Poly(ADP-ribose) Polymerases
Descriptor Spanish: Poli(ADP-Ribosa) Polimerasas
Descriptor poli(ADP-ribosa) polimerasas
Entry term(s) ADP-ribosiltransferasa (polimerizante)
poli ADP-ribosa polimerasa
poli(ADP-ribosa) polimerasa
poli(ADP-ribosa) sintetasa
Scope note: Enzimas que catalizan la transferencia de múltiples grupos ADP RIBOSA del dinucleótido de nicotinamida-adenina (NAD) a proteínas diana, formando un homopolímero lineal o ramificado de unidades de ADP-ribosa repetidas, es decir, POLI ADENOSINA DIFOSFATO RIBOSA.
Descriptor Portuguese: Poli(ADP-Ribose) Polimerases
Descriptor French: Poly(ADP-ribose) polymerases
Entry term(s): ADP-Ribosyltransferase (Polymerizing)
PARP Polymerase
Poly ADP Ribose Polymerase
Poly ADP Ribose Synthase
Poly ADP Ribose Transferase
Poly ADP-Ribose Synthase
Poly(ADP-Ribose) Synthase
Poly(ADP-Ribose) Transferase
Poly(ADP-ribose) Polymerase
Poly(ADPR) Polymerase
Poly(ADPribose) Polymerase
Polymerase, PARP
Synthase, Poly ADP-Ribose
Tree number(s): D08.811.913.400.725.115.690
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011065
Scope note: Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleotide (NAD) onto protein targets, thus building up a linear or branched homopolymer of repeating ADP-ribose units i.e., POLY ADENOSINE DIPHOSPHATE RIBOSE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Poly(ADP-ribose) Polymerase Inhibitors
Registry Number: EC 2.4.2.30
CAS Type 1 Name: NAD+:poly(adenosine diphosphate D-ribose)-acceptor ADP-D-ribosyltransferase
Previous Indexing: NAD Nucleosidase (1975-1976)
Nucleosidases (1966-1974)
Public MeSH Note: 2003 (1977); see NAD+ ADP-RIBOSYLTRANSFERASE 1992-2002, see POLY ADP RIBOSE POLYMERASE 1977-1991, see NAD NUCLEOSIDASE 1975-1976
History Note: 2003 (1977); use NAD NUCLEOSIDASE 1975-1976
Related: Poly ADP Ribosylation MeSH
DeCS ID: 30405
Unique ID: D011065
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1986/01/01
Date of Entry: 1976/04/19
Revision Date: 2017/04/14
Poly(ADP-ribose) Polymerases - Preferred
Concept UI M0017141
Scope note Enzymes that catalyze the transfer of multiple ADP-RIBOSE groups from nicotinamide-adenine dinucleotide (NAD) onto protein targets, thus building up a linear or branched homopolymer of repeating ADP-ribose units i.e., POLY ADENOSINE DIPHOSPHATE RIBOSE.
Preferred term Poly(ADP-ribose) Polymerases
Entry term(s) ADP-Ribosyltransferase (Polymerizing)
PARP Polymerase
Poly ADP Ribose Polymerase
Poly ADP Ribose Synthase
Poly ADP Ribose Transferase
Poly ADP-Ribose Synthase
Poly(ADP-Ribose) Synthase
Poly(ADP-Ribose) Transferase
Poly(ADP-ribose) Polymerase
Poly(ADPR) Polymerase
Poly(ADPribose) Polymerase
Polymerase, PARP
Synthase, Poly ADP-Ribose



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