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Descriptor English: Pseudomonas aeruginosa Exotoxin A
Descriptor Spanish: Exotoxina A de Pseudomonas aeruginosa
Descriptor exotoxina A de Pseudomonas aeruginosa
Entry term(s) PE38QQR
exotoxina A recombinante truncada de Pseudomonas, forma PE38QQR
exotoxina A recombinante truncada de Pseudomonas, forma PE40
toxina PE40
Scope note: ADP-ribosiltransferasa dependiente de NAD que cataliza la transferencia de la porción ADP-ribosil del NAD oxidado al factor de elongación 2 (EF-2), deteniendo así la síntesis de proteínas. Se utiliza habitualmente como toxina en inmunotoxinas.
Descriptor Portuguese: Exotoxina A de Pseudomonas aeruginosa
Descriptor French: Without translation
Entry term(s): ETA, Pseudomonas
Exotoxin A, Pseudomonas
Exotoxin A, Pseudomonas aeruginosa
PE38QQR
PE40 toxin
Recombinant Truncated Pseudomonas Exotoxin A, Form PE38QQR
Recombinant Truncated Pseudomonas Exotoxin A, Form PE40
ToxA protein, Pseudomonas aeruginosa
Tree number(s): D08.811.913.400.725.115.826
D23.946.123.574
D23.946.350.625
D23.946.896.245
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000097668
Scope note: An NAD-dependent ADP-ribosyltransferase that catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD onto elongation factor 2 (EF-2) thus arresting protein synthesis. Commonly used as the toxin in immunotoxins.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.4.2.31
Public MeSH Note: PSEUDOMONAS AERUGINOSA EXOTOXIN A was indexed under BACTERIAL TOXINS, EXOTOXINS, ADP RIBOSE TRANSFERASES and VIRULENCE FACTORS 2022-2023
History Note: 2024 (2022)
DeCS ID: 60629
Unique ID: D000097668
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/06/12
Pseudomonas aeruginosa Exotoxin A - Preferred
Concept UI M000758363
Scope note An NAD-dependent ADP-ribosyltransferase that catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD onto elongation factor 2 (EF-2) thus arresting protein synthesis. Commonly used as the toxin in immunotoxins.
Preferred term Pseudomonas aeruginosa Exotoxin A
Entry term(s) ETA, Pseudomonas
Exotoxin A, Pseudomonas
Exotoxin A, Pseudomonas aeruginosa
ToxA protein, Pseudomonas aeruginosa
Recombinant Truncated Pseudomonas Exotoxin A, Form PE40 - Narrower
Concept UI M000758365
Preferred term Recombinant Truncated Pseudomonas Exotoxin A, Form PE40
Entry term(s) PE40 toxin
Recombinant Truncated Pseudomonas Exotoxin A, Form PE38QQR - Narrower
Concept UI M000758364
Preferred term Recombinant Truncated Pseudomonas Exotoxin A, Form PE38QQR
Entry term(s) PE38QQR



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