| Descriptor English: | Ribonucleoprotein, U1 Small Nuclear | ||||||
| Descriptor Spanish: |
Ribonucleoproteína Nuclear Pequeña U1
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| Descriptor Portuguese: | Ribonucleoproteína Nuclear Pequena U1 | ||||||
| Descriptor French: | Petites ribonucléoprotéines nucléaires U1 | ||||||
| Entry term(s): |
Ribonucleoproteins, Small, U1 Small Nuclear Ribonucleoproteins, U1 U1 Small Nuclear Ribonucleoproteins U1 snRNP |
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| Tree number(s): |
D12.776.157.725.500.875.600 D12.776.157.725.829.313 D12.776.664.962.500.875.600 D12.776.664.962.829.313 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D017412 | ||||||
| Scope note: | A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Ribonucleoproteins (1975-1992) |
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| Public MeSH Note: | 2000; RIBONUCLEOPROTEINS, SMALL, U1 was heading 1993-1999; U1-RNP was indexed under RIBONUCLEOPROTEINS 1982-92 |
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| History Note: | 2000; U1 SNRNP was U1-RNP (SY) to SMALL RIBONUCLEOPROTEINS (NM) 1982-92 |
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| DeCS ID: | 30535 | ||||||
| Unique ID: | D017412 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1993/01/01 | ||||||
| Date of Entry: | 1992/05/22 | ||||||
| Revision Date: | 2016/07/05 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Ribonucleoprotein, U1 Small Nuclear
- Preferred
| Concept UI |
M0026429 |
| Scope note | A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U1 snRNP along with other small nuclear ribonucleoproteins (U2, U4-U6, and U5) assemble into SPLICEOSOMES that remove introns from pre-mRNA by splicing. The U1 snRNA forms base pairs with conserved sequence motifs at the 5'-splice site and recognizes both the 5'- and 3'-splice sites and may have a fundamental role in aligning the two sites for the splicing reaction. |
| Preferred term | Ribonucleoprotein, U1 Small Nuclear |
| Entry term(s) |
Ribonucleoproteins, Small, U1 Small Nuclear Ribonucleoproteins, U1 U1 Small Nuclear Ribonucleoproteins U1 snRNP |
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