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Descriptor English: Prostate-Specific Antigen
Descriptor Spanish: Antígeno Prostático Específico
Descriptor antígeno prostático específico
Entry term(s) antígeno específico de la próstata
antígeno específico prostático
calicreína hK3
gamma seminoproteína
gamma-seminoproteína
seminoproteína gamma
seminoproteína-gamma
Scope note: Glucoproteína que es una serina proteinasa similar a la calicreína y es sintetizada por las células epiteliales del tejido prostático, tanto normal como maligno. Es un marcador importante para el diagnóstico del cáncer de próstata.
Descriptor Portuguese: Antígeno Prostático Específico
Descriptor French: Antigène spécifique de la prostate
Entry term(s): Kallikrein hK3
Kallikrein, hK3
Prostate Specific Antigen
Semenogelase
Seminin
gamma Seminoprotein
gamma-Seminoprotein
hK3 Kallikrein
Tree number(s): D08.811.277.656.300.760.442.750
D08.811.277.656.959.350.442.750
D12.776.869.250.249.500
D23.050.285.625
D23.101.140.625
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017430
Scope note: A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.21.77
Previous Indexing: Antigens, Neoplasm (1982-1992)
Public MeSH Note: 93; PROSTATE CANCER SPECIFIC ANTIGENS was indexed under ANTIGENS, NEOPLASM 1982-92; SEMENOGELASE was indexed under PROSTATE-SPECIFIC ANTIGEN 1988-95 & PEPTIDE PEPTIDOHYDROLASE 1976-87
Online Note: use PROSTATE-SPECIFIC ANTIGEN (NM) to search PROSTATE CANCER SPECIFIC ANTIGENS 1982-92 & SEMENOGELASE 1980-95
History Note: 93; was PROSTATE CANCER SPECIFIC ANTIGENS (NM) 1982-92; SEMENOGELASE was NM 1976-95
Related: Prostatic Neoplasms MeSH
DeCS ID: 30596
Unique ID: D017430
NLM Classification: WJ 762
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/22
Revision Date: 2015/06/19
Prostate-Specific Antigen - Preferred
Concept UI M0026444
Scope note A glycoprotein that is a kallikrein-like serine proteinase and an esterase, produced by epithelial cells of both normal and malignant prostate tissue. It is an important marker for the diagnosis of prostate cancer.
Preferred term Prostate-Specific Antigen
Entry term(s) Kallikrein hK3
Kallikrein, hK3
Prostate Specific Antigen
Semenogelase
Seminin
gamma Seminoprotein
gamma-Seminoprotein
hK3 Kallikrein



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