Search
Descriptor English: Pancreatitis-Associated Proteins
Descriptor Spanish: Proteínas Asociadas a Pancreatitis
Descriptor proteínas asociadas a pancreatitis
Entry term(s) proteína 1 asociada a pancreatitis
proteína 3 derivada de los islotes de regeneración
proteína asociada a pancreatitis
proteína derivada de los islotes de regeneración
proteínas derivadas de los islotes de regeneración
Scope note: Lectinas de tipo C que limitan el crecimiento de bacterias en el epitelio intestinal y tienen actividad bactericida frente a bacterias grampositivas y gramnegativas. También regulan la proliferación y diferenciación de los QUERATINOCITOS después de una lesión. La proteína 1 asociada a pancreatitis humana (Reg3a) se sobreexpresa en las CÉLULAS ACINARES pancreáticas en pacientes con PANCREATITIS CRÓNICA. Su expresión también está aumentada en las células del cáncer de páncreas, de vesícula y gastrointestinal y puede servir como biomarcador diagnóstico.
Descriptor Portuguese: Proteínas Associadas a Pancreatite
Descriptor French: Protéines associées à la pancréatite
Entry term(s): Pancreatitis Associated Protein
Pancreatitis Associated Protein 1
Pancreatitis Associated Proteins
Pancreatitis-Associated Protein
Pancreatitis-Associated Protein-1
Regenerating Islet Derived Protein 3
Regenerating Islet Derived Proteins
Regenerating Islet-Derived Protein
Regenerating Islet-Derived Protein 3
Regenerating Islet-Derived Proteins
Tree number(s): D12.776.503.280.578
D23.050.285.733
D23.101.140.780
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000073718
Scope note: C-type lectins that restrict growth of bacteria in the intestinal epithelia and have bactericidal activity against gram-positive and gram-negative bacteria. They also regulate proliferation and differentiation of KERATINOCYTES following injury. Human pancreatitis-associated protein-1 (Reg3a) is overexpressed by pancreatic ACINAR CELLS in patients with CHRONIC PANCREATITIS. It is also highly expressed by pancreatic, bladder, and gastrointestinal cancer cells and may serve as a diagnostic biomarker.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2018; PANCREATITIS-ASSOCIATED PROTEINS was indexed under PROTEINS 1992-1995, ACUTE-PHASE PROTEINS 1996-2001, CALCIUM-BINDING PROTEINS 2002 and LECTINS, C-TYPE 2003-2017
History Note: 2018 (1992)
DeCS ID: 57130
Unique ID: D000073718
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/01/17
Pancreatitis-Associated Proteins - Preferred
Concept UI M000623679
Scope note C-type lectins that restrict growth of bacteria in the intestinal epithelia and have bactericidal activity against gram-positive and gram-negative bacteria. They also regulate proliferation and differentiation of KERATINOCYTES following injury. Human pancreatitis-associated protein-1 (Reg3a) is overexpressed by pancreatic ACINAR CELLS in patients with CHRONIC PANCREATITIS. It is also highly expressed by pancreatic, bladder, and gastrointestinal cancer cells and may serve as a diagnostic biomarker.
Preferred term Pancreatitis-Associated Proteins
Entry term(s) Pancreatitis Associated Proteins
Regenerating Islet Derived Proteins
Regenerating Islet-Derived Protein
Regenerating Islet-Derived Proteins
Pancreatitis-Associated Protein-1 - Narrower
Concept UI M0195484
Preferred term Pancreatitis-Associated Protein-1
Entry term(s) Pancreatitis Associated Protein
Pancreatitis Associated Protein 1
Pancreatitis-Associated Protein
Regenerating Islet Derived Protein 3
Regenerating Islet-Derived Protein 3



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.


Go to survey