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Descriptor English: CD52 Antigen
Descriptor Spanish: Antígeno CD52
Descriptor antígeno CD52
Entry term(s) HLA-Bw52
antígeno CDw52
antígeno Cambridge pathology 1
antígeno Campath-1
antígeno Campath-1H
antígeno HLA-Bw52
antígeno linfocitario CD52
antígeno linfocitario CDw52
proteína CD52
receptor Campath-1
Scope note: Pequeña glucoproteína ligada a GPI que se expresa en la superficie de los LINFOCITOS B, LINFOCITOS T, MONOCITOS, MACRÓFAGOS, CÉLULAS NK y GRANULOCITOS normales y malignos. Se expresa ampliamente y sin modulación en muchas neoplasias malignas de linfocitos T y es por tanto un objetivo para los tratamientos con anticuerpos (p. ej., ALEMTUZUMAB).
Descriptor Portuguese: Antígeno CD52
Descriptor French: Antigène CD52
Entry term(s): CD52 Protein
CD52, Lymphocyte Antigen
CDw52 Antigen
CDw52, Lymphocyte Antigen
Cambridge Pathology 1 Antigen
Campath 1 Antigen
Campath 1 Receptor
Campath 1H Antigen
Campath-1 Antigen
Campath-1 Receptor
Campath-1H Antigen
HLA Bw52
HLA Bw52 Antigen
HLA-Bw52
HLA-Bw52 Antigen
Lymphocyte Antigen CD52
Lymphocyte Antigen CDw52
Tree number(s): D09.400.430.890.448.190
D12.776.395.550.448.190
D12.776.543.484.500.190
D12.776.543.550.418.190
D23.050.285.022
D23.101.100.943
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000074301
Scope note: A small GPI-linked glycoprotein expressed on the surface of normal and malignant B-CELLS; T-CELLS; MONOCYTES; MACROPHAGES; NK CELLS; and GRANULOCYTES. It is expressed densely and without modulation in many malignant T-cell neoplasms and therefore a target for antibody therapies (e.g., ALEMTUZUMAB).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Antigens, CD (1991-2017)
Antigens, Neoplasm (1991-2017)
Glycoproteins (1991-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 57128
Unique ID: D000074301
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/04/10
CD52 Antigen - Preferred
Concept UI M000626116
Scope note A small GPI-linked glycoprotein expressed on the surface of normal and malignant B-CELLS; T-CELLS; MONOCYTES; MACROPHAGES; NK CELLS; and GRANULOCYTES. It is expressed densely and without modulation in many malignant T-cell neoplasms and therefore a target for antibody therapies (e.g., ALEMTUZUMAB).
Preferred term CD52 Antigen
Entry term(s) CD52 Protein
CD52, Lymphocyte Antigen
CDw52 Antigen
CDw52, Lymphocyte Antigen
Cambridge Pathology 1 Antigen
Campath 1 Antigen
Campath 1 Receptor
Campath 1H Antigen
Campath-1 Antigen
Campath-1 Receptor
Campath-1H Antigen
HLA Bw52
HLA Bw52 Antigen
HLA-Bw52
HLA-Bw52 Antigen
Lymphocyte Antigen CD52
Lymphocyte Antigen CDw52



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