| Descriptor English: | Carbonic Anhydrase IX | ||||||
| Descriptor Spanish: |
Anhidrasa Carbónica IX
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| Descriptor Portuguese: | Anidrase Carbônica IX | ||||||
| Descriptor French: | Carbonic anhydrase IX | ||||||
| Entry term(s): |
CAIX Protein Carbonic Anhydrase 9 |
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| Tree number(s): |
D08.811.520.241.300.150.450 D12.776.543.178 D23.050.285.196 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000071231 | ||||||
| Scope note: | A carbonic anhydrase and transmembrane protein that consists of an N-terminal PROTEOGLYCAN-like domain, a catalytic region, a single-pass transmembrane domain, and a short intracellular tail. It functions as a dimer and is expressed primarily by cells of the GASTROINTESTINAL TRACT; BILE DUCT EPITHELIUM; and GALL BLADDER. It is expressed at high levels in many solid tumors, especially CLEAR CELL RENAL CARCINOMA, in response to CELL HYPOXIA. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 4.2.1.1 | ||||||
| Previous Indexing: |
Antigens, Neoplasm (1994-2016) Carbonic Anhydrases (1994-2016) |
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| Public MeSH Note: | 2017 |
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| History Note: | 2017 |
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| DeCS ID: | 56498 | ||||||
| Unique ID: | D000071231 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2017/01/01 | ||||||
| Date of Entry: | 2016/07/08 | ||||||
| Revision Date: | 2016/02/25 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Carbonic Anhydrase IX
- Preferred
| Concept UI |
M000613753 |
| Scope note | A carbonic anhydrase and transmembrane protein that consists of an N-terminal PROTEOGLYCAN-like domain, a catalytic region, a single-pass transmembrane domain, and a short intracellular tail. It functions as a dimer and is expressed primarily by cells of the GASTROINTESTINAL TRACT; BILE DUCT EPITHELIUM; and GALL BLADDER. It is expressed at high levels in many solid tumors, especially CLEAR CELL RENAL CARCINOMA, in response to CELL HYPOXIA. |
| Preferred term | Carbonic Anhydrase IX |
| Entry term(s) |
CAIX Protein Carbonic Anhydrase 9 |
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