Descriptor English: | Apoptosis | ||||||
Descriptor Spanish: |
Apoptosis
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Descriptor Portuguese: | Apoptose | ||||||
Descriptor French: | Apoptose | ||||||
Entry term(s): |
Apoptoses, Extrinsic Pathway Apoptoses, Intrinsic Pathway Apoptosis, Caspase-Dependent Apoptosis, Classic Apoptosis, Classical Apoptosis, Extrinsic Pathway Apoptosis, Intrinsic Pathway Caspase Dependent Apoptosis Caspase-Dependent Apoptosis Cell Death, Programmed Classic Apoptoses Classic Apoptosis Classical Apoptosis Extrinsic Pathway Apoptoses Extrinsic Pathway Apoptosis Intrinsic Pathway Apoptoses Intrinsic Pathway Apoptosis Programmed Cell Death Programmed Cell Death, Type I |
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Tree number(s): |
G04.146.954.035 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D017209 | ||||||
Scope note: | A regulated cell death mechanism characterized by distinctive morphologic changes in the nucleus and cytoplasm, including the endonucleolytic cleavage of genomic DNA, at regularly spaced, internucleosomal sites, i.e., DNA FRAGMENTATION. It is genetically-programmed and serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth. |
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Annotation: | general or unspecified, note specifics |
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Allowable Qualifiers: |
DE drug effects GE genetics IM immunology PH physiology RE radiation effects |
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Previous Indexing: |
Cell Survival (1972-1992) |
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Public MeSH Note: | 93 |
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History Note: | 93 |
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Related: |
CARD Signaling Adaptor Proteins
MeSH Caspases MeSH Cellular Apoptosis Susceptibility Protein MeSH Death Domain Receptor Signaling Adaptor Proteins MeSH Genes, Transgenic, Suicide MeSH In Situ Nick-End Labeling MeSH Necrosis MeSH | ||||||
DeCS ID: | 30827 | ||||||
Unique ID: | D017209 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1993/01/01 | ||||||
Date of Entry: | 1992/05/07 | ||||||
Revision Date: | 2020/06/09 |
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PHENOMENA AND PROCESSES
Cell Physiological Phenomena [G04]Cell Physiological Phenomena
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Apoptosis
- Preferred
Apoptosis, Intrinsic Pathway
- Narrower
Apoptosis, Extrinsic Pathway
- Narrower
Programmed Cell Death
- Narrower
Caspase-Dependent Apoptosis
- Narrower
Concept UI |
M0026116 |
Scope note | A regulated cell death mechanism characterized by distinctive morphologic changes in the nucleus and cytoplasm, including the endonucleolytic cleavage of genomic DNA, at regularly spaced, internucleosomal sites, i.e., DNA FRAGMENTATION. It is genetically-programmed and serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth. |
Preferred term | Apoptosis |
Entry term(s) |
Apoptosis, Classic Apoptosis, Classical Classic Apoptoses Classic Apoptosis Classical Apoptosis Programmed Cell Death, Type I |
Concept UI |
M0493497 |
Scope note | Apoptosis that is triggered via cell stress and mitochondrial damage. |
Preferred term | Apoptosis, Intrinsic Pathway |
Entry term(s) |
Apoptoses, Intrinsic Pathway Intrinsic Pathway Apoptoses Intrinsic Pathway Apoptosis |
Concept UI |
M0493496 |
Scope note | Apoptosis that is triggered via CELL SURFACE RECEPTORS such as TUMOR NECROSIS FACTOR RECEPTORS and DEATH DOMAIN RECEPTORS. |
Preferred term | Apoptosis, Extrinsic Pathway |
Entry term(s) |
Apoptoses, Extrinsic Pathway Extrinsic Pathway Apoptoses Extrinsic Pathway Apoptosis |
Concept UI |
M000644348 |
Scope note | Physiological forms of regulated cell death that occur during growth and development and tissue turnover. |
Preferred term | Programmed Cell Death |
Entry term(s) |
Cell Death, Programmed |
Concept UI |
M000675620 |
Preferred term | Caspase-Dependent Apoptosis |
Entry term(s) |
Apoptosis, Caspase-Dependent Caspase Dependent Apoptosis |
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