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Descriptor English: Germ-Line Mutation
Descriptor Spanish: Mutación de Línea Germinal
Descriptor mutación de la línea germinal
Scope note: Cualquier alteración hereditaria detectable en la línea germinal. Las mutaciones en estas células (es decir, las células generadoras ancestros de los gametos) se transmiten a la progenie en tanto que las mutaciones de las células somáticas no se transmiten.
Descriptor Portuguese: Mutação em Linhagem Germinativa
Descriptor French: Mutation germinale
Entry term(s): Germ Line Mutation
Germ-Line Mutations
Germline Mutation
Germline Mutations
Mutation, Germ Line
Mutation, Germ-Line
Mutation, Germline
Mutations, Germ-Line
Mutations, Germline
Tree number(s): G05.365.590.350
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018095
Scope note: Any detectable and heritable alteration in the lineage of germ cells. Mutations in these cells (i.e., "generative" cells ancestral to the gametes) are transmitted to progeny while those in somatic cells are not.
Annotation: germ-line refers to germ cells (ovum or spermatozoon), not micro-organisms
Allowable Qualifiers: DE drug effects
ES ethics
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Mutation (1980-1993)
Public MeSH Note: 94
History Note: 94
DeCS ID: 31443
Unique ID: D018095
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1993/06/03
Revision Date: 2008/07/08
Germ-Line Mutation - Preferred
Concept UI M0027291
Scope note Any detectable and heritable alteration in the lineage of germ cells. Mutations in these cells (i.e., "generative" cells ancestral to the gametes) are transmitted to progeny while those in somatic cells are not.
Preferred term Germ-Line Mutation
Entry term(s) Germ Line Mutation
Germ-Line Mutations
Germline Mutation
Germline Mutations
Mutation, Germ Line
Mutation, Germ-Line
Mutation, Germline
Mutations, Germ-Line
Mutations, Germline



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