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Descriptor English: Founder Effect
Descriptor Spanish: Efecto Fundador
Descriptor Portuguese: Efeito Fundador
Descriptor French: Effet fondateur
Entry term(s): Effect, Founder
Effects, Founder
Founder Effects
Tree number(s): G05.285
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018703
Scope note: A phenomenon that is observed when a small subgroup of a larger POPULATION establishes itself as a separate and isolated entity. The subgroup's GENE POOL carries only a fraction of the genetic diversity of the parental population resulting in an increased frequency of certain diseases in the subgroup, especially those diseases known to be autosomal recessive.
Previous Indexing: Genetics, Population (1969-1983)
Pedigree (1983-1994)
Public MeSH Note: 95
History Note: 95
Entry Version: FOUNDER EFF
DeCS ID: 32244
Unique ID: D018703
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1995/01/01
Date of Entry: 1994/04/19
Revision Date: 2008/07/08
Founder Effect - Preferred
Concept UI M0028017
Scope note A phenomenon that is observed when a small subgroup of a larger POPULATION establishes itself as a separate and isolated entity. The subgroup's GENE POOL carries only a fraction of the genetic diversity of the parental population resulting in an increased frequency of certain diseases in the subgroup, especially those diseases known to be autosomal recessive.
Preferred term Founder Effect
Entry term(s) Effect, Founder
Effects, Founder
Founder Effects



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