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Descriptor English: Platelet Glycoprotein GPIb-IX Complex
Descriptor Spanish: Complejo GPIb-IX de Glicoproteína Plaquetaria
Descriptor complejo GPIb-IX de glicoproteína plaquetaria
Entry term(s) antígenos CD42a
antígenos CD42b
antígenos CD42c
antígenos CD42d
Scope note: Complejo glicoproteico plaquetario esencial para la normal adhesión de las plaquetas y la formación del coágulo en los puntos donde existen lesiones vasculares. Está constituido por tres polipéptidos, el GPIb alfa, el GPIb beta y el GPIX. Una glicopropteína Ib actúa como receptor del factor Von Willebrand y la trombina. El déficit congénito del complejo GPIb-IX da lugar al síndrome de Bernard-Soulier. La glicoproteína GPV asociada a GPIb-IX tambien está ausente en el síndrome de Bernard-Soulier.
Descriptor Portuguese: Complexo Glicoproteico GPIb-IX de Plaquetas
Descriptor French: Complexe glycoprotéique GPIb-IX plaquettaire
Entry term(s): Antigen, CD42a
Antigen, CD42b
Antigen, CD42c
Antigen, CD42d
Antigens, CD42a
Antigens, CD42b
Antigens, CD42c
Antigens, CD42d
CD42a Antigen
CD42a Antigens
CD42b Antigen
CD42b Antigens
CD42c Antigen
CD42c Antigens
CD42d Antigen
CD42d Antigens
Glycoprotein Ib
Glycoprotein Ib IX Complex
Glycoprotein Ib alpha
Glycoprotein Ib beta
Glycoprotein Ib-IX Complex
Platelet Glycoprotein GPIb IX Complex
Platelet Glycoprotein IX
Platelet Membrane Glycoprotein IX
Platelet Membrane Glycoprotein Ib
Platelet Membrane Glycoprotein V
Tree number(s): D12.776.395.550.625.460
D12.776.543.550.625.460
D12.776.543.750.705.675.568
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019038
Scope note: Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides, GPIb alpha, GPIb beta, and GPIX. Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin. Congenital deficiency of the GPIb-IX complex results in Bernard-Soulier syndrome. The platelet glycoprotein GPV associates with GPIb-IX and is also absent in Bernard-Soulier syndrome.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: deficiency:Bernard-Soulier Syndrome
Previous Indexing: Platelet Membrane Glycoproteins (1987-1995)
Public MeSH Note: 96; PLATELET MEMBRANE GLYCOPROTEIN IB was see PLATELET MEMBRANE GLYCOPROTEINS 1987-95
Online Note: use PLATELET MEMBRANE GLYCOPROTEINS to search PLATELET MEMBRANE GLYCOPROTEIN IB 1987-95
History Note: 96; PLATELET MEMBRANE GLYCOPROTEIN IB was see PLATELET MEMBRANE GLYCOPROTEINS 1987-95
Entry Version: GPIB IX
DeCS ID: 32648
Unique ID: D019038
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1996/01/01
Date of Entry: 1995/05/26
Revision Date: 2015/06/25
Platelet Glycoprotein GPIb-IX Complex - Preferred
Concept UI M0028417
Scope note Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides, GPIb alpha, GPIb beta, and GPIX. Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin. Congenital deficiency of the GPIb-IX complex results in Bernard-Soulier syndrome. The platelet glycoprotein GPV associates with GPIb-IX and is also absent in Bernard-Soulier syndrome.
Preferred term Platelet Glycoprotein GPIb-IX Complex
Entry term(s) Glycoprotein Ib IX Complex
Glycoprotein Ib-IX Complex
Platelet Glycoprotein GPIb IX Complex
Platelet Membrane Glycoprotein Ib - Narrower
Concept UI M0028418
Preferred term Platelet Membrane Glycoprotein Ib
Entry term(s) Glycoprotein Ib
CD42c Antigens - Narrower
Concept UI M0028422
Preferred term CD42c Antigens
Entry term(s) Antigen, CD42c
Antigens, CD42c
CD42c Antigen
Glycoprotein Ib beta
CD42b Antigens - Narrower
Concept UI M0028421
Preferred term CD42b Antigens
Entry term(s) Antigen, CD42b
Antigens, CD42b
CD42b Antigen
Glycoprotein Ib alpha
Platelet Membrane Glycoprotein V - Related but not broader or narrower
Concept UI M0028420
Preferred term Platelet Membrane Glycoprotein V
CD42d Antigen - Narrower
Concept UI M0028423
Preferred term CD42d Antigen
Entry term(s) Antigen, CD42d
Antigens, CD42d
CD42d Antigens
Platelet Membrane Glycoprotein IX - Narrower
Concept UI M0028419
Preferred term Platelet Membrane Glycoprotein IX
Entry term(s) Antigen, CD42a
Antigens, CD42a
CD42a Antigen
CD42a Antigens
Platelet Glycoprotein IX



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