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Descriptor English: Transcription Factors, TFII
Descriptor Spanish: Factores de Transcripción TFII
Descriptor factores de transcripción TFII
Scope note: Son los denominados factores generales de transcripción que se unen a la ARN POLIMERASA II y que son necesarios para iniciar la transcripción. Ellos incluyen a TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, TFII-I, y TFIIJ. Aparentemente, in vivo, se unen en un proceso de pasos múltiples y ordenados y/o pueden formar un gran complejo de preiniciación denominado holoenzima ARN polimerasa II.
Descriptor Portuguese: Fatores de Transcrição TFII
Descriptor French: Facteurs de transcription TFII
Entry term(s): TFII Transcription Factors
Tree number(s): D12.776.260.775.875
D12.776.930.930.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019473
Scope note: The so-called general transcription factors that bind to RNA POLYMERASE II and that are required to initiate transcription. They include TFIIA; TFIIB; TFIID; TFIIE; TFIIF; TFIIH; TFII-I; and TFIIJ. In vivo they apparently bind in an ordered multi-step process and/or may form a large preinitiation complex called RNA polymerase II holoenzyme.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Transcription Factors (1979-1996)
Public MeSH Note: 97
History Note: 97
DeCS ID: 33064
Unique ID: D019473
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1997/01/01
Date of Entry: 1996/06/10
Revision Date: 2005/06/30
Transcription Factors, TFII - Preferred
Concept UI M0028965
Scope note The so-called general transcription factors that bind to RNA POLYMERASE II and that are required to initiate transcription. They include TFIIA; TFIIB; TFIID; TFIIE; TFIIF; TFIIH; TFII-I; and TFIIJ. In vivo they apparently bind in an ordered multi-step process and/or may form a large preinitiation complex called RNA polymerase II holoenzyme.
Preferred term Transcription Factors, TFII
Entry term(s) TFII Transcription Factors



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