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Descriptor English: Transcription Factors, General
Descriptor Spanish: Factores Generales de Transcripción
Descriptor factores generales de transcripción
Scope note: Factores de transcripción que forman complejos de iniciación de la transcripción en el ADN, se unen a POLIMERASAS DE ARN DIRIGIDAS POR ADN específicas y son necesarios para iniciar la transcripción. Aunque su unión puede estar localizada en secuencias y motivos estructurales concretos dentro del ADN, se les considera inespecíficos en relación con el gen específico que ha de transcribirse.
Descriptor Portuguese: Fatores Genéricos de Transcrição
Descriptor French: Facteurs généraux de transcription
Entry term(s): General Transcription Factors
General Transcription Initiation Complex Proteins
Tree number(s): D12.776.260.775
D12.776.930.930
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D035165
Scope note: Transcription factors that form transcription initiation complexes on DNA, bind to specific DNA-DIRECTED RNA POLYMERASES and are required to initiate transcription. Although their binding may be localized to distinct sequence and structural motifs within the DNA they are considered non-specific with regard to the specific gene being transcribed.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2003
History Note: 2003
DeCS ID: 37429
Unique ID: D035165
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2013/07/09
Transcription Factors, General - Preferred
Concept UI M0198210
Scope note Transcription factors that form transcription initiation complexes on DNA, bind to specific DNA-DIRECTED RNA POLYMERASES and are required to initiate transcription. Although their binding may be localized to distinct sequence and structural motifs within the DNA they are considered non-specific with regard to the specific gene being transcribed.
Preferred term Transcription Factors, General
Entry term(s) General Transcription Factors
General Transcription Initiation Complex Proteins - Related but not broader or narrower
Concept UI M0407610
Preferred term General Transcription Initiation Complex Proteins



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