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Descriptor English: TATA-Box Binding Protein
Descriptor Spanish: Proteína de Unión a TATA-Box
Descriptor proteína de unión a TATA-box
Scope note: Factor de transcripción general que desempeña un papel principal en la activación de los genes eucarióticos, transcritos por ARN POLIMERASAS. Se une específicamente al elemento promotor de TATA BOX, situado muy próximo a la posición de la iniciación de la transcripción en el ARN transcrito por la ARN POLIMERASA II. Aunque considerado como componente principal del FACTOR DE TRANSCRIPCIÓN TFIID, participa también en los complejos generales de factores de transcripción implicados en la transcripción de ARN POLIMERASA I y ARN POLIMERASA II.
Descriptor Portuguese: Proteína de Ligação a TATA-Box
Descriptor French: Protéine de liaison à la boite TATA
Entry term(s): RNA Polymerase II TATA Binding Protein
RNA Polymerase II TATA-Binding Protein
TATA Binding Protein
TATA Box Binding Protein
TATA-Binding Protein
TATA-Box-Binding Protein
Transcription Factor TBP
Tree number(s): D12.776.260.775.374
D12.776.260.775.875.750.500
D12.776.930.930.374
D12.776.930.930.875.750.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D035181
Scope note: A general transcription factor that plays a major role in the activation of eukaryotic genes transcribed by RNA POLYMERASES. It binds specifically to the TATA BOX promoter element, which lies close to the position of transcription initiation in RNA transcribed by RNA POLYMERASE II. Although considered a principal component of TRANSCRIPTION FACTOR TFIID it also takes part in general transcription factor complexes involved in RNA POLYMERASE I and RNA POLYMERASE III transcription.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: DNA-Binding Proteins (1992-2002)
Transcription Factors (1992-2002)
Public MeSH Note: 2003; TATA-BOX BINDING PROTEIN was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1992-2002
History Note: 2003; use TATA-BOX BINDING PROTEIN (NM) 1992-2002
DeCS ID: 37432
Unique ID: D035181
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2005/06/30
TATA-Box Binding Protein - Preferred
Concept UI M0406970
Scope note A general transcription factor that plays a major role in the activation of eukaryotic genes transcribed by RNA POLYMERASES. It binds specifically to the TATA BOX promoter element, which lies close to the position of transcription initiation in RNA transcribed by RNA POLYMERASE II. Although considered a principal component of TRANSCRIPTION FACTOR TFIID it also takes part in general transcription factor complexes involved in RNA POLYMERASE I and RNA POLYMERASE III transcription.
Preferred term TATA-Box Binding Protein
Entry term(s) RNA Polymerase II TATA Binding Protein
RNA Polymerase II TATA-Binding Protein
TATA Binding Protein
TATA Box Binding Protein
TATA-Binding Protein
TATA-Box-Binding Protein
Transcription Factor TBP



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