| Descriptor English: | Tissue Inhibitor of Metalloproteinase-1 | ||||||
| Descriptor Spanish: |
Inhibidor Tisular de Metaloproteinasa-1
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| Descriptor Portuguese: | Inibidor Tecidual de Metaloproteinase-1 | ||||||
| Descriptor French: | Inhibiteur tissulaire de métalloprotéinase-1 | ||||||
| Entry term(s): |
Metalloproteinase-1 Tissue Inhibitor TIMP-1 Tissue Inhibitor of Metalloproteinase 1 |
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| Tree number(s): |
D12.776.815.875.450 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D019715 | ||||||
| Scope note: | A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a N-glycosylated protein, molecular weight 28 kD, produced by a vast range of cell types and found in a variety of tissues and body fluids. It has been shown to suppress metastasis and inhibit tumor invasion in vitro. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Pharm Action: |
Matrix Metalloproteinase Inhibitors |
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| Previous Indexing: |
Glycoproteins (1990-1997) |
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| Public MeSH Note: | 98; COLLAGENASE INHIBITOR (now TISSUE-INHIBITOR OF METALLOPROTEINASE-1) was indexed under GLYCOPROTEINS 1990-97 |
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| History Note: | 98; see TISSUE-INHIBITOR OF METALLOPROTEINASE-1 (NM) 1980-97 |
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| Entry Version: | TISSUE INHIB METALLOPROTEINASE 1 |
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| DeCS ID: | 33426 | ||||||
| Unique ID: | D019715 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1998/01/01 | ||||||
| Date of Entry: | 1997/06/20 | ||||||
| Revision Date: | 2012/07/03 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Tissue Inhibitor of Metalloproteinase-1
- Preferred
| Concept UI |
M0029271 |
| Scope note | A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a N-glycosylated protein, molecular weight 28 kD, produced by a vast range of cell types and found in a variety of tissues and body fluids. It has been shown to suppress metastasis and inhibit tumor invasion in vitro. |
| Preferred term | Tissue Inhibitor of Metalloproteinase-1 |
| Entry term(s) |
Metalloproteinase-1 Tissue Inhibitor TIMP-1 Tissue Inhibitor of Metalloproteinase 1 |
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