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Descriptor English: Proteinase Inhibitory Proteins, Secretory
Descriptor Spanish: Proteínas Inhibidoras de Proteinasas Secretoras
Descriptor proteínas segregadas inhibidoras de proteinasas
Entry term(s) inhibidor de la elastasa de los neutrófilos
inhibidores de elastasa neutrofílica
inhibidores de la elastasa neutrofílica
péptidos inhibidores de proteinasas secretoras
péptidos segregados inhibidores de proteinasas
Scope note: Péptidos y proteínas que se encuentran en las SECRECIONES CORPORALES y en los LÍQUIDOS CORPORALES que son INHIBIDORES DE PROTEASAS. Desempeñan un papel en la INFLAMACIÓN, reparación tisular e inmunidad innata (INMUNIDAD INNATA) al inhibir las proteinasas endógenas tales como las producidas por los LEUCOCITOS y proteasas exógenas tales como las producidas por los microorganismos invasores.
Descriptor Portuguese: Proteínas Secretadas Inibidoras de Proteinases
Descriptor French: Protéines sécrétoires inhibitrices de protéinases
Entry term(s): Elastase Inhibitor, Neutrophil
Elastase Inhibitors, Neutrophil
Inhibitor, Neutrophil Elastase
Inhibitors, Neutrophil Elastase
Neutrophil Elastase Inhibitor
Neutrophil Elastase Inhibitors
Peptidase Inhibitory Peptides, Secretory
Peptidase Inhibitory Proteins, Secretory
Protease Inhibitory Peptides, Secretory
Protease Inhibitory Proteins, Secretory
Proteinase Inhibitory Peptides, Secretory
Tree number(s): D12.644.822
D12.776.815
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053491
Scope note: Peptides and proteins found in BODILY SECRETIONS and BODY FLUIDS that are PROTEASE INHIBITORS. They play a role in INFLAMMATION, tissue repair and innate immunity (IMMUNITY, INNATE) by inhibiting endogenous proteinases such as those produced by LEUKOCYTES and exogenous proteases such as those produced by invading microorganisms.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Protease Inhibitors
Public MeSH Note: 2007; NEUTROPHIL ELASTASE INHIBITORS was indexed under PROTEINS 1996-2006, under SERINE PROTEINASE INHIBITORS 1990-1995, under PROTEASE INHIBITORS 1980-1989, under ENZYME INHIBITORS 1978-1979, & under PEPTIDE PEPTIDOHYDROLASES 1978-1979
History Note: 2007(1980)
Related: Protease Inhibitors MeSH
DeCS ID: 52317
Unique ID: D053491
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2020/05/27
Proteinase Inhibitory Proteins, Secretory - Preferred
Concept UI M0493685
Scope note Peptides and proteins found in BODILY SECRETIONS and BODY FLUIDS that are PROTEASE INHIBITORS. They play a role in INFLAMMATION, tissue repair and innate immunity (IMMUNITY, INNATE) by inhibiting endogenous proteinases such as those produced by LEUKOCYTES and exogenous proteases such as those produced by invading microorganisms.
Preferred term Proteinase Inhibitory Proteins, Secretory
Entry term(s) Peptidase Inhibitory Proteins, Secretory
Protease Inhibitory Proteins, Secretory
Proteinase Inhibitory Peptides, Secretory - Related but not broader or narrower
Concept UI M0493736
Preferred term Proteinase Inhibitory Peptides, Secretory
Entry term(s) Peptidase Inhibitory Peptides, Secretory
Protease Inhibitory Peptides, Secretory
Neutrophil Elastase Inhibitors - Narrower
Concept UI M0485530
Preferred term Neutrophil Elastase Inhibitors
Entry term(s) Elastase Inhibitor, Neutrophil
Elastase Inhibitors, Neutrophil
Inhibitor, Neutrophil Elastase
Inhibitors, Neutrophil Elastase
Neutrophil Elastase Inhibitor



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