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Descriptor English: Ryanodine Receptor Calcium Release Channel
Descriptor Spanish: Canal Liberador de Calcio Receptor de Rianodina
Descriptor canal liberador de calcio del receptor de rianodina
Entry term(s) RyR1
complejo receptor de calcio-rianodina
receptor 1 de rianodina
receptor 2 de rianodina
receptor 3 de rianodina
receptores de rianodina
Scope note: Canal de liberación de calcio tetramérico que se encuentra en la membrana del RETÍCULO SARCOPLASMÁTICO de las CÉLULAS MUSCULARES LISAS. Tiene una acción opuesta a la de las ATPASAS TRANSPORTADORAS DE CALCIO DEL RETÍCULO SARCOPLASMÁTICO. Es importante en el acoplamiento excitación-contracción esquelética y cardíaca y se ha estudiado usando RIANODINA. Las anomalías de este canal están implicadas en ARRITMIAS CARDIACAS y en ENFERMEDADES MUSCULARES.
Descriptor Portuguese: Canal de Liberação de Cálcio do Receptor de Rianodina
Descriptor French: Canal de libération du calcium du récepteur à la ryanodine
Entry term(s): Ca Release Channel Ryanodine Receptor
Ca Release Channel-Ryanodine Receptor
Calcium Ryanodine Receptor Complex
Calcium-Ryanodine Receptor Complex
Complex, Calcium-Ryanodine Receptor
Receptor 1, Ryanodine
Receptor 2, Ryanodine
Receptor 3, Ryanodine
Receptor Complex, Calcium-Ryanodine
Receptor, Ryanodine
Receptors, Ryanodine
RyR1
RyR2
RyR3
Ryanodine Receptor
Ryanodine Receptor 1
Ryanodine Receptor 2
Ryanodine Receptor 3
Ryanodine Receptors
Tree number(s): D12.776.157.530.400.150.800
D12.776.210.500.800
D12.776.543.550.450.150.800
D12.776.543.585.400.150.800
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019837
Scope note: A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Calcium Channel Blockers
agonists:Calcium Channel Agonists
Previous Indexing: Calcium Channels (1988-1997)
Muscle Proteins (1993-1997)
Receptors, Cholinergic (1985-1992)
Public MeSH Note: 98; CALCIUM-RYANODINE RECEPTOR COMPLEX (now RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL) was indexed under CALCIUM CHANNELS 1988-97, MUSCLE PROTEINS 1993-97, & RECEPTORS, CHOLINERGIC 1985-92
History Note: 98; use RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL (NM) 1985-97
Entry Version: RYANODINE RECEPT CALCIUM RELEASE CHANNEL
DeCS ID: 33489
Unique ID: D019837
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2016/07/01
Ryanodine Receptor Calcium Release Channel - Preferred
Concept UI M0029444
Scope note A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.
Preferred term Ryanodine Receptor Calcium Release Channel
Entry term(s) Ca Release Channel Ryanodine Receptor
Ca Release Channel-Ryanodine Receptor
Calcium Ryanodine Receptor Complex
Calcium-Ryanodine Receptor Complex
Complex, Calcium-Ryanodine Receptor
Receptor Complex, Calcium-Ryanodine
Receptor, Ryanodine
Ryanodine Receptor
Ryanodine Receptors - Broader
Concept UI M0029445
Preferred term Ryanodine Receptors
Entry term(s) Receptors, Ryanodine
Ryanodine Receptor 3 - Narrower
Concept UI M0029447
Preferred term Ryanodine Receptor 3
Entry term(s) Receptor 3, Ryanodine
RyR3
Ryanodine Receptor 1 - Narrower
Concept UI M0029448
Preferred term Ryanodine Receptor 1
Entry term(s) Receptor 1, Ryanodine
RyR1
Ryanodine Receptor 2 - Narrower
Concept UI M0029446
Preferred term Ryanodine Receptor 2
Entry term(s) Receptor 2, Ryanodine
RyR2



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