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Descriptor English: Cytotoxins
Descriptor Spanish: Citotoxinas
Descriptor citotoxinas
Entry term(s) agente citotóxico
agentes citotóxicos
citolisinas
citotoxina
sustancias citotóxicas
Scope note: Sustancias que son tóxicas para las células. Pueden intervenir en la inmunidad o pueden formar parte de venenos. Se distinguen de los CITOSTÁTICOS en el grado de efecto. Algunas se utilizan como ANTIBIÓTICOS CITOTÓXICOS. Muchos de ellos actúan como ALQUILANTES o MODULADORES DE LA MITOSIS.
Descriptor Portuguese: Citotoxinas
Descriptor French: Cytotoxines
Entry term(s): Agent, Cytotoxic
Cytolysins
Cytotoxic Agent
Cytotoxic Agents
Cytotoxin
Tree number(s): D27.888.569.213
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003603
Scope note: Substances that are toxic to cells; they may be involved in immunity or may be contained in venoms. These are distinguished from CYTOSTATIC AGENTS in degree of effect. Some of them are used as CYTOTOXIC ANTIBIOTICS. The mechanism of action of many of these are as ALKYLATING AGENTS or MITOSIS MODULATORS.
Annotation: /antag permitted but consider also ANTITOXINS; coordinate with source of cytotoxin
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Cytotoxicity Tests, Immunologic (1973-1977)
Toxins (1966-1977)
specific cell (1966-1977)
Public MeSH Note: 78
History Note: 78
Related: Antineoplastic Agents MeSH
Cytostatic Agents MeSH
DeCS ID: 3622
Unique ID: D003603
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1978/01/01
Date of Entry: 1977/04/22
Revision Date: 2020/05/27
Cytotoxins - Preferred
Concept UI M0005633
Scope note Substances that are toxic to cells; they may be involved in immunity or may be contained in venoms. These are distinguished from CYTOSTATIC AGENTS in degree of effect. Some of them are used as CYTOTOXIC ANTIBIOTICS. The mechanism of action of many of these are as ALKYLATING AGENTS or MITOSIS MODULATORS.
Preferred term Cytotoxins
Entry term(s) Agent, Cytotoxic
Cytotoxic Agent
Cytotoxic Agents
Cytotoxin
Cytolysins - Narrower
Concept UI M0005632
Preferred term Cytolysins



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