| Descriptor in English: | Epothilones |
| Descriptor in Spanish: | Epotilonas |
| Descriptor in Portuguese: | Epotilonas |
| Descriptor in French: | Épothilones |
| Entry term(s): |
Epothilon Epothilone |
| Tree number(s): |
D02.540.576.500.984 |
| Scope note: | A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES). |
| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
| History Note: | 2003 |
| DeCS UI: | 37309 |
| Descriptor UI: | D034261 |
| Date Established: | 2003/01/01 |
| Date of Entry: | 2002/07/03 |
| Revision Date: | 2015/06/22 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals
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Epothilones
- Preferred
| Concept UI |
M0405146 |
| Scope note | A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES). |
| Preferred term | Epothilones |
| Entry term(s) |
Epothilon Epothilone |
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