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Descriptor in English: Epothilones
Descriptor in Spanish: Epotilonas
Descriptor in Portuguese: Epotilonas
Descriptor in French: Épothilones
Entry term(s): Epothilon
Epothilone
Tree number(s): D02.540.576.500.984
Scope note: A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 2003
DeCS UI: 37309
Descriptor UI: D034261
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2015/06/22
Epothilones - Preferred
Concept UI M0405146
Scope note A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES).
Preferred term Epothilones
Entry term(s) Epothilon
Epothilone



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