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Descriptor English: Epothilones
Descriptor Spanish: Epotilonas
Descriptor epotilonas
Scope note: Grupo de MACRÓLIDOS de 16 miembros que estabilizan los MICROTÚBULOS de modo similar a como lo hace el PACLITAXEL. Fuenton encontrados originalmente en la mixobacteria Sorangium cellulosum, renombrada en la actualidad en Polyangium (MYXOCOCCALES).
Descriptor Portuguese: Epotilonas
Descriptor French: Épothilones
Entry term(s): Epothilon
Epothilone
Tree number(s): D02.540.576.500.984
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D034261
Scope note: A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Tubulin Modulators
Previous Indexing: Epoxy Compounds (1995-2002)
Macrolides (1998-2002)
Public MeSH Note: 2003
History Note: 2003
DeCS ID: 37309
Unique ID: D034261
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2015/06/22
Epothilones - Preferred
Concept UI M0405146
Scope note A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES).
Preferred term Epothilones
Entry term(s) Epothilon
Epothilone



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