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Descriptor English: Brefeldin A
Descriptor Spanish: Brefeldino A
Descriptor brefeldina A
Scope note: Metabolito de los hongos, el cual es una lactona macrocíclica que exhibe un amplio espectro de actividad antibiótica.
Descriptor Portuguese: Brefeldina A
Descriptor French: Bréfeldine A
Entry term(s): Ascotoxin
Cyanein
Decumbin
NSC 89671
NSC-89671
NSC89671
Synergisidin
Tree number(s): D02.540.576.500.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020126
Scope note: A fungal metabolite which is a macrocyclic lactone exhibiting a wide range of antibiotic activity.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Antifungal Agents
Antiviral Agents
Protein Synthesis Inhibitors
Registry Number: 20350-15-6
CAS Type 1 Name: 4H-Cyclopent(f)oxacyclotridecin-4-one,1,6,7,8,9,11a-beta,12,13,14,14a-alpha-decahydro-1-beta-13-alpha-dihydroxy-6-beta-methyl-
Previous Indexing: Cyclopentanes (1974-1998)
Public MeSH Note: 99; BREFELDIN A was indexed under CYCLOPENTANES 1974-98
History Note: 99; use BREFELDIN A (NM) 1980-98
DeCS ID: 33808
Unique ID: D020126
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1999/01/01
Date of Entry: 1998/06/10
Revision Date: 2015/06/22
Brefeldin A - Preferred
Concept UI M0029866
Scope note A fungal metabolite which is a macrocyclic lactone exhibiting a wide range of antibiotic activity.
Preferred term Brefeldin A
Entry term(s) Ascotoxin
Cyanein
Decumbin
Synergisidin
NSC-89671 - Narrower
Concept UI M0352003
Preferred term NSC-89671
Entry term(s) NSC 89671
NSC89671



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