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Descriptor English: Filipin
Descriptor Spanish: Filipina
Descriptor filipina
Entry term(s) filipina III
Scope note: Complejo de antibióticos poliénicos obtenidos de Streptomyces filipinensis. La filipina III altera la función de la membrana al interferir con los esteroles de la membrana, inhibe la respiración mitocondrial y ha sido propuesto como agente antifúngico. Las filipinas I, II y IV son menos importantes.
Descriptor Portuguese: Filipina
Descriptor French: Filipine
Entry term(s): Desoxylagosin
Filimarisin
Filipin I
Filipin II
Filipin III
Filipin IV
NSC 3364
NSC-3364
NSC3364
U 5956
U-5956
U5956
Tree number(s): D02.455.326.271.665.325
D02.540.576.500.996
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005372
Scope note: A complex of polyene antibiotics obtained from Streptomyces filipinensis. Filipin III alters membrane function by interfering with membrane sterols, inhibits mitochondrial respiration, and is proposed as an antifungal agent. Filipins I, II, and IV are less important.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Bacterial Agents
Antifungal Agents
Antiviral Agents
Registry Number: 87Z59R7D14
Previous Indexing: Fatty Acids, Essential (1966-1971)
Fatty Acids, Unsaturated (1972-1974)
Lactones (1966-1974)
Polyenes (1966-1974)
Public MeSH Note: 91; was see under ANTIBIOTICS, ANTIFUNGAL 1990-90; was see under POLYENES 1975-89
History Note: 91(75); was see under ANTIBIOTICS, ANTIFUNGAL 1990-90; was see under POLYENES 1975-89
DeCS ID: 29392
Unique ID: D005372
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2015/06/22
Filipin - Preferred
Concept UI M0008473
Scope note A complex of polyene antibiotics obtained from Streptomyces filipinensis. Filipin III alters membrane function by interfering with membrane sterols, inhibits mitochondrial respiration, and is proposed as an antifungal agent. Filipins I, II, and IV are less important.
Preferred term Filipin
Entry term(s) Desoxylagosin
Filimarisin
Filipin III
Filipin II - Related but not broader or narrower
Concept UI M0008475
Preferred term Filipin II
NSC-3364 - Narrower
Concept UI M0351805
Preferred term NSC-3364
Entry term(s) NSC 3364
NSC3364
U-5956 - Narrower
Concept UI M0351804
Preferred term U-5956
Entry term(s) U 5956
U5956
Filipin I - Related but not broader or narrower
Concept UI M0008474
Preferred term Filipin I
Filipin IV - Related but not broader or narrower
Concept UI M0008476
Preferred term Filipin IV



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