| Descriptor English: | Stathmin | ||||||
| Descriptor Spanish: |
Estatmina
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| Descriptor Portuguese: | Estatmina | ||||||
| Descriptor French: | Stathmine | ||||||
| Entry term(s): |
Alpha Stathmin Alpha-Stathmin Beta Stathmin Beta-Stathmin Lap18 Protein Leukemia Associated Phosphoprotein p18 Leukemia-Associated Phosphoprotein p18 Metablastin Oncoprotein 18 Op18 Phosphoprotein Op18a Protein Op18b Protein Phosphoprotein p18 Phosphoprotein p19 Phosphoprotein, Op18 Prosolin p18, Leukemia-Associated Phosphoprotein p18, Phosphoprotein p19, Phosphoprotein |
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| Tree number(s): |
D12.776.220.600.450.480 D12.776.624.664.700.957 D12.776.744.772 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D050777 | ||||||
| Scope note: | A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2006; STATHMIN was indexed under MICROTUBULE PROTEINS & PHOSPHOPROTEINS 1987-2005 |
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| History Note: | 2006(1987) |
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| DeCS ID: | 50938 | ||||||
| Unique ID: | D050777 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2006/01/01 | ||||||
| Date of Entry: | 2005/06/30 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Stathmin
- Preferred
Beta-Stathmin
- Narrower
Alpha-Stathmin
- Narrower
| Concept UI |
M0166763 |
| Scope note | A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS. |
| Preferred term | Stathmin |
| Entry term(s) |
Lap18 Protein Leukemia Associated Phosphoprotein p18 Leukemia-Associated Phosphoprotein p18 Metablastin Oncoprotein 18 Op18 Phosphoprotein Phosphoprotein p18 Phosphoprotein p19 Phosphoprotein, Op18 Prosolin p18, Leukemia-Associated Phosphoprotein p18, Phosphoprotein p19, Phosphoprotein |
| Concept UI |
M0166754 |
| Preferred term | Beta-Stathmin |
| Entry term(s) |
Beta Stathmin Op18b Protein |
| Concept UI |
M0166753 |
| Preferred term | Alpha-Stathmin |
| Entry term(s) |
Alpha Stathmin Op18a Protein |
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