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Descriptor English: Integrin alpha4beta1
Descriptor Spanish: Integrina alfa4beta1
Descriptor integrina alfa4beta1
Scope note: Fibronectina (FIBRONECTINAS) y receptor VCAM-1 presente en los LINFOCITOS, MONOCITOS, EOSINÓFILOS, CÉLULAS NK y timocitos. Está implicada tanto en la adhesión de la MATRIZ EXTRACELULAR-célula como de célula-célula y tiene una función en la INFLAMACIÓN, función inmune y de ubicación de la célula hematopoyética y ha sido implicada en la MIOGÉNESIS esquelética, la migración de la CRESTA NEURAL y la proliferación, maduración linfocítica y morfogénesis de la PLACENTA y el CORAZÓN.
Descriptor Portuguese: Integrina alfa4beta1
Descriptor French: Intégrine alpha4bêta1
Entry term(s): Antigen-4, Very Late
CD49d-CD29
Heterodimer alpha4beta1, Integrin
Integrin Heterodimer alpha4beta1
Integrin alpha(4)beta(1)
Integrin, alpha4beta1
Late Antigen-4, Very
VLA-4
Very Late Activation Antigen 4
Very Late Activation Antigen-4
Very Late Antigen 4
Very Late Antigen-4
alpha4beta1 Integrin
alpha4beta1, Integrin
alpha4beta1, Integrin Heterodimer
Tree number(s): D09.400.430.890.200.625.347
D12.776.395.550.200.625.347
D12.776.543.550.200.625.347
D12.776.543.750.705.408.530.500
D12.776.543.750.705.408.850.299
D12.776.543.750.705.877.347
D23.050.301.350.625.347
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D039041
Scope note: Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in both cell-cell and cell- EXTRACELLULAR MATRIX adhesion and plays a role in INFLAMMATION, hematopoietic cell homing and immune function, and has been implicated in skeletal MYOGENESIS; NEURAL CREST migration and proliferation, lymphocyte maturation and morphogenesis of the PLACENTA and HEART.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Integrins (1991-2002)
Receptors, Lymphocyte Homing (1991-2002)
Public MeSH Note: 2003; INTEGRIN ALPHA4BETA1 was indexed under INTEGRINS and RECEPTORS, LYMPHOCYTE HOMING 1991-2002
History Note: 2003 (1991)
DeCS ID: 37448
Unique ID: D039041
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/02
Revision Date: 2017/05/24
Integrin alpha4beta1 - Preferred
Concept UI M0184906
Scope note Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in both cell-cell and cell- EXTRACELLULAR MATRIX adhesion and plays a role in INFLAMMATION, hematopoietic cell homing and immune function, and has been implicated in skeletal MYOGENESIS; NEURAL CREST migration and proliferation, lymphocyte maturation and morphogenesis of the PLACENTA and HEART.
Preferred term Integrin alpha4beta1
Entry term(s) Antigen-4, Very Late
CD49d-CD29
Heterodimer alpha4beta1, Integrin
Integrin Heterodimer alpha4beta1
Integrin alpha(4)beta(1)
Integrin, alpha4beta1
Late Antigen-4, Very
VLA-4
Very Late Activation Antigen 4
Very Late Activation Antigen-4
Very Late Antigen 4
Very Late Antigen-4
alpha4beta1 Integrin
alpha4beta1, Integrin
alpha4beta1, Integrin Heterodimer



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