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Descriptor English: CD11c Antigen
Descriptor Spanish: Antígeno CD11c
Descriptor antígeno CD11c
Entry term(s) antígenos CD11c
antígenos Leu-M5
integrina alfaX
Scope note: Subunidad de integrina alfa con un peso melecular aproximado de 150-kDa. Se expresa en grandes cantidades en los monocitos y se combina con el ANTÍGENO CD18 para formar el receptor de superficie celular INTEGRINA ALFAXBETA2. La subunidad conserva un dominio I característico de algunas integrinas alfa.
Descriptor Portuguese: Antígeno CD11c
Descriptor French: Antigènes CD11c
Entry term(s): Antigen, CD11c
Antigens, CD11c
Antigens, Leu-M5
CD11c Antigens
Integrin alphaX
Leu M5 Antigens
Leu-M5 Antigens
alphaX, Integrin
Tree number(s): D09.400.430.890.200.074.875
D09.400.430.890.200.275.500
D12.776.395.550.200.074.875
D12.776.395.550.200.275.500
D12.776.543.550.200.093.875
D12.776.543.550.200.275.500
D12.776.543.750.705.408.100.200
D12.776.543.750.705.408.600.100.500
D12.776.543.750.705.833.249.500
D23.050.301.350.074.074
D23.050.301.350.275.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D039521
Scope note: An integrin alpha subunit of approximately 150-kDa molecular weight. It is expressed at high levels on monocytes and combines with CD18 ANTIGEN to form the cell surface receptor INTEGRIN ALPHAXBETA2. The subunit contains a conserved I-domain which is characteristic of several of alpha integrins.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Integrin alphaXbeta2 (1995-2002)
Public MeSH Note: 2018; see ANTIGENS, CD11C 2003-2018; for CD11C ANTIGEN and ANTIGENS, CD11C see COMPLEMENT 4-BINDING PROTEIN 1995-2002
History Note: 2018 (1995); for CD11C ANTIGEN and ANTIGENS, CD11C use INTEGRIN ALPHAXBETA2 1995-2002
DeCS ID: 37485
Unique ID: D039521
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/02
Revision Date: 2017/05/24
CD11c Antigen - Preferred
Concept UI M0024680
Scope note An integrin alpha subunit of approximately 150-kDa molecular weight. It is expressed at high levels on monocytes and combines with CD18 ANTIGEN to form the cell surface receptor INTEGRIN ALPHAXBETA2. The subunit contains a conserved I-domain which is characteristic of several of alpha integrins.
Preferred term CD11c Antigen
Entry term(s) Antigen, CD11c
Antigens, CD11c
Antigens, Leu-M5
CD11c Antigens
Integrin alphaX
Leu M5 Antigens
Leu-M5 Antigens
alphaX, Integrin



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