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Descriptor English: Platelet Membrane Glycoprotein IIb
Descriptor Spanish: Glicoproteína IIb de Membrana Plaquetaria
Descriptor glicoproteína IIb de membrana plaquetaria
Entry term(s) antígenos CD41
integrina alfaIIb
Scope note: Subunidad alfa de la integrina que heterodimeriza con la INTEGRINA BETA3 para formar el COMPLEJO GPIIB-IIIA DE GLICOPREOTEÍNA PLAQUETARIA. Se sintetiza como una cadena polipeptídica única, que es escindida tras la traducción y procesada en dos subunidades unidas a disulfuro de aproximadamente 18 y 110 kDa de tamaño.
Descriptor Portuguese: Glicoproteína IIb da Membrana de Plaquetas
Descriptor French: Glycoprotéine-IIb de membrane plaquettaire
Entry term(s): Antigen, CD41
Antigen, HUPL-ml Surface
Antigens, CD41
CD41 Antigen
CD41 Antigens
CD41 Cell Surface Antigen
GP IIb
GPalpha IIb
Glycoprotein IIb, Membrane
HUPL ml Surface Antigen
HUPL-ml Surface Antigen
Integrin alpha IIb
Integrin alphaIIb
Membrane Glycoprotein IIb
Plasma Membrane Glycoprotein IIb
Surface Antigen, HUPL-ml
alphaIIb, Integrin
Tree number(s): D12.776.543.750.705.408.100.950
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D040201
Scope note: Platelet membrane glycoprotein IIb is an integrin alpha subunit that heterodimerizes with INTEGRIN BETA3 to form PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX. It is synthesized as a single polypeptide chain which is then postranslationally cleaved and processed into two disulfide-linked subunits of approximately 18 and 110 kDa in size.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Integrins (1992-1995)
Platelet Glycoprotein GPIIb-IIIa Complex (1996-2002)
Platelet Membrane Glycoproteins (1987-2002)
Public MeSH Note: 2003; see PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX 1996-2002
History Note: 2003; use PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX 1996-2002
Related: Platelet Glycoprotein GPIIb-IIIa Complex MeSH
DeCS ID: 37493
Unique ID: D040201
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/02
Revision Date: 2017/05/24
Platelet Membrane Glycoprotein IIb - Preferred
Concept UI M0028425
Scope note Platelet membrane glycoprotein IIb is an integrin alpha subunit that heterodimerizes with INTEGRIN BETA3 to form PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX. It is synthesized as a single polypeptide chain which is then postranslationally cleaved and processed into two disulfide-linked subunits of approximately 18 and 110 kDa in size.
Preferred term Platelet Membrane Glycoprotein IIb
Entry term(s) Antigen, CD41
Antigen, HUPL-ml Surface
Antigens, CD41
CD41 Antigen
CD41 Antigens
CD41 Cell Surface Antigen
GP IIb
GPalpha IIb
Glycoprotein IIb, Membrane
HUPL ml Surface Antigen
HUPL-ml Surface Antigen
Integrin alpha IIb
Integrin alphaIIb
Membrane Glycoprotein IIb
Plasma Membrane Glycoprotein IIb
Surface Antigen, HUPL-ml
alphaIIb, Integrin



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