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Descriptor English: Integrin alpha5
Descriptor Spanish: Integrina alfa5
Descriptor integrina alfa5
Entry term(s) antígenos CD49e
Scope note: Esta subunidad de integrina alfa se combina con la INTEGRINA BETA1 para formar un receptor (INTEGRINA ALFA5BETA1) que se une a la FIBRONECTINA y la LAMININA. Experimenta clivaje postraduccional para dar una cadena pesada y otra ligera que están conectadas por puentes disulfuro.
Descriptor Portuguese: Integrina alfa5
Descriptor French: Intégrine alpha5
Entry term(s): Antigen, CD49e
Antigens, CD49e
CD49e Antigen
CD49e Antigens
Glycoprotein Ic, Platelet
Ic, Platelet Glycoprotein
Integrin alphaF
Integrin, alpha5
Platelet Glycoprotein Ic
VLA 5 alpha Chain
VLA-5 alpha Chain
alpha Chain, VLA-5
alpha(5) Integrin
alpha5 Integrin
alpha5, Integrin
alphaF, Integrin
Tree number(s): D12.776.543.750.705.408.100.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D039482
Scope note: This integrin alpha subunit combines with INTEGRIN BETA1 to form a receptor (INTEGRIN ALPHA5BETA1) that binds FIBRONECTIN and LAMININ. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PO poisoning
RE radiation effects
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Antigens, CD (1996-2002)
Public MeSH Note: 2003; INTEGRIN ALPHA5 was indexed under ANTIGENS, CD 1996-2002
History Note: 2003 (1996)
DeCS ID: 37490
Unique ID: D039482
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/02
Revision Date: 2017/05/24
Integrin alpha5 - Preferred
Concept UI M0247642
Scope note This integrin alpha subunit combines with INTEGRIN BETA1 to form a receptor (INTEGRIN ALPHA5BETA1) that binds FIBRONECTIN and LAMININ. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds.
Preferred term Integrin alpha5
Entry term(s) Antigen, CD49e
Antigens, CD49e
CD49e Antigen
CD49e Antigens
Glycoprotein Ic, Platelet
Ic, Platelet Glycoprotein
Integrin alphaF
Integrin, alpha5
Platelet Glycoprotein Ic
VLA 5 alpha Chain
VLA-5 alpha Chain
alpha Chain, VLA-5
alpha(5) Integrin
alpha5 Integrin
alpha5, Integrin
alphaF, Integrin



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