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Descriptor English: Methenyltetrahydrofolate Cyclohydrolase
Descriptor Spanish: Meteniltetrahidrofolato Ciclohidrolasa
Descriptor meteniltetrahidrofolato ciclohidrolasa
Scope note: Aminohidrolasa que cataliza la hidrólisis del 5,10-meteniltetrahidrofolato para dar 10-formiltetrahidrofolato. En la mayoría de los organismos eucariotas superiores esta enzima también incluye las actividades de la METILENOTETRAHIDROFOLATO DESHIDROGENASA (NADP) y FORMATO-TETRAHIDROFOLATO LIGASA.
Descriptor Portuguese: Meteniltetra-Hidrofolato Cicloidrolase
Descriptor French: Methenyltetrahydrofolate cyclohydrolase
Entry term(s): 5,10 MTHF Cyclohydrolase
5,10 Methenyltetrahydrofolate Cyclohydrolase
5,10-MTHF Cyclohydrolase
5,10-Methenyltetrahydrofolate 5-Hydrolase (Decyclizing)
5,10-Methenyltetrahydrofolate Cyclohydrolase
Cyclohydrolase, 5,10-MTHF
Cyclohydrolase, 5,10-Methenyltetrahydrofolate
Cyclohydrolase, Methenyltetrahydrofolate
Tree number(s): D08.811.277.151.418
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D045064
Scope note: An aminohydrolase that catalyzes the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate. In most higher eucaryotic organisms this enzyme also includes METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NADP) and FORMATE-TETRAHYDROFOLATE LIGASE activities.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.5.4.9
Previous Indexing: Aminohydrolases (1983-2003)
Hydrolases (1974-1977)
Tetrahydrofolates (1974-1982)
Public MeSH Note: 2004; METHENYLTETRAHYDRODROFOLATE CYCLOHYDROLASE was indexed under AMINOHYDROLASES 1983-2003, under TETRAHYDROFOLATES 1974-1982, under HYDROLASES 1974-1977
History Note: 2004; use METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE (NM) 1980-2003
Related: Formate-Tetrahydrofolate Ligase MeSH
Methylenetetrahydrofolate Dehydrogenase (NADP) MeSH
DeCS ID: 38138
Unique ID: D045064
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Methenyltetrahydrofolate Cyclohydrolase - Preferred
Concept UI M0076651
Scope note An aminohydrolase that catalyzes the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate. In most higher eucaryotic organisms this enzyme also includes METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NADP) and FORMATE-TETRAHYDROFOLATE LIGASE activities.
Preferred term Methenyltetrahydrofolate Cyclohydrolase
Entry term(s) 5,10 MTHF Cyclohydrolase
5,10 Methenyltetrahydrofolate Cyclohydrolase
5,10-MTHF Cyclohydrolase
5,10-Methenyltetrahydrofolate 5-Hydrolase (Decyclizing)
5,10-Methenyltetrahydrofolate Cyclohydrolase
Cyclohydrolase, 5,10-MTHF
Cyclohydrolase, 5,10-Methenyltetrahydrofolate
Cyclohydrolase, Methenyltetrahydrofolate



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